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Displaying results 11 - 20 of 6970 in total
  1. Drug

    Caspofungin

    go.drugbank.com/drugs/DB00520
    ApprovedInvestigational

    Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against...

    Categories: Antimycotics for Systemic Use, Antiinfectives for Systemic UseProducts: FUPASCIN POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 70MG/VIAL, FUPASCIN POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG/VIAL
  2. Drug

    Ertapenem

    go.drugbank.com/drugs/DB00303
    ApprovedInvestigational

    [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: ERTAPENEM MEVON POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 1G/VIAL, Ertapenem for Injection
  3. Drug

    Bendamustine

    go.drugbank.com/drugs/DB06769
    ApprovedInvestigational

    Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). Bendamustine is a bifunctional mechlorethamine derivative capable of formi...

    Products: BEMUNAT POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 25 MG/VIAL USP, BEMUNAT POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100 MG/VIAL USP
  4. Drug

    Etanercept

    go.drugbank.com/drugs/DB00005
    ApprovedInvestigational

    Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.

    Categories: Biologics for Rheumatoid Arthritis TreatmentProducts: BENEPALI 25MG FER, BENEPALI 50MG FER
  5. Drug

    Teprotumumab

    go.drugbank.com/drugs/DB06343
    ApprovedInvestigational

    which its efficacy in the treatment of thyroid eye disease (TED) was assessed, it received "breakthrough therapy" designation from the FDA in 2016[A190129] and was approved by the FDA in January 2020 for … Graves' Disease involving inflammation and tissue remodeling behind the eye, and previous treatment options typically involved multiple invasive surgeries - teprotumumab is the first drug ever approved for

    Synonyms: Immunoglobulin G1, anti-(human insulin-like growth factor I receptor) (human monoclonal heavy chain), disulfide with human monoclonal light chain, dimerCategories: Insulin-like Growth Factor-1 Receptor Inhibitor
  6. Drug

    Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate

    go.drugbank.com/drugs/DB14106
    ApprovedInvestigational

    Tetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for assessing myocardial perfusion.[L12744]

    Products: Kit for the Preparation of Technetium Tc99m Sestamibi, MIBITEC 1 mg Kit für ein radioaktives Arzneimittel
  7. Drug

    Golimumab

    go.drugbank.com/drugs/DB06674
    ApprovedInvestigational

    Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with moderate to severe active rheumatoid arthritis (RA), (ii) alone or as an adjunct to methotrexate

    Categories: Biologics for Rheumatoid Arthritis Treatment, Tumor Necrosis Factor Receptor Blocking ActivityProducts: Concentrate for Solution for Infusion 12.5mg/1 ml, SIMPONI 100MG FER
  8. Drug

    Sotatercept

    go.drugbank.com/drugs/DB12118
    ApprovedInvestigational

    [L50351] On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension (PAH). … It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain.

    Synonyms: ACTIVIN RECEPTOR TYPE IIA (SYNTHETIC HUMAN EXTRACELLULAR DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER, (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-Categories: Antihypertensives for Pulmonary Arterial Hypertension
  9. Drug

    Pemetrexed

    go.drugbank.com/drugs/DB00642
    ApprovedInvestigational

    It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative

    Products: PODOXRED POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 500MG, EMETA 500mg Powder for Concentrate for Solution for Infusion
  10. Drug

    Anidulafungin

    go.drugbank.com/drugs/DB00362
    Approved

    Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366. There is preliminary evidence that it has a s...

    Categories: Antimycotics for Systemic Use, Antiinfectives for Systemic UseProducts: ANIDACCORD 100 POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100 MG, Eraxis 100mg For Injection