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Mitapivat

Mitapivat is a novel, first-in-class pyruvate kinase activator. It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival of red blood cells. … [A245478] On January 5, 2026, the FDA also approved the use of in the treatment of anemia in adults with alpha- or beta-thalassemia, making it the first oral treatment for this condition.[L54953]

Bitolterol

Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. It is a beta-2-adrenergic receptor agonist. Bitolterol was withdrawn from the market by Elan Pharmaceuticals in 2001.

3-O-Methylfructose in Linear Form

1,6-Di-O-Phosphono-D-Allitol

Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen

matrix proteins, all of which are known to be involved in wound repair. … [L35525] Stratagraft consists of two kinds of lab-grown skin cells, keratinocytes and dermal fibroblasts, which are grown together on a murine collagen matrix to make a bi-layered construct (i.e. a

1,6-DI-O-PHOSPHONO-D-MANNITOL

2,3-di-O-phytanyl-sn-glycerol

QazCovid-in

It demonstrated high efficacy, safety, and immunogenicity at 96% in initial Phase I and II trials (NCT04530357), and will now be undergoing upcoming Phase III trials[L30633, L30638]. … The QazCovid-in vaccine, an inactivated vaccine, was developed and tested in the Kazakh Research Institute for Biological Safety Problems[L30628].

Metocurine

Dimethyltubocurarinium (INN) or metocurine (USAN), also known as dimethyltubocurarine, is a non-depolarizing muscle relaxant. … Patients on chronic anticonvulsant drugs are relatively resistant to metocurine. [A2393]

Lorazepam

[A957] It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977. … Lorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic.