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Displaying results 191 - 200 of 10000 in total
  1. Drug

    Lisinopril

    go.drugbank.com/drugs/DB00722
    ApprovedInvestigational

    [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. … Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.

    Synonyms: [N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline, (S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-prolineMixtures: Lisinopril-HCT G.L. 20mg/25mg - Tabletten, LISIPLUS AL 20MG/12.5MG
  2. Drug

    Racepinephrine

    go.drugbank.com/drugs/DB11124
    Approved

    Racepinephrine is a racemic mixture consisting of d-[DB00668] and l-[DB00668] enantiomers. Epinephrine is a non-selective α- and β-adrenergic receptor agonist. … It is an active ingredient in oral inhalation over-the-counter products as racepinephrine hydrochloride.

    Mixtures: Gingicord W Epineph and Alum Size No 1, Gingicord W Epineph and Alum Size No 3Categories: Epinephrine and similars, Alpha-and Beta-adrenergic Agonists
  3. Drug

    Nitrofurantoin

    go.drugbank.com/drugs/DB00698
    ApprovedInvestigationalVet approved

    [L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. … [A179824] This drug is more resistant to the development of bacterial resistance because it acts on many targets at once.

    Synonyms: N-(5-Nitrofurfurylidene)-1-aminohydantoinProducts: Macrodantin Cap 25mg, Novo-furan Sus 25mg/5ml
  4. Drug

    Pseudoephedrine

    go.drugbank.com/drugs/DB00852
    Approved

    Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system. … [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889.

    Mixtures: IBUCOLD PLUS 100MG+15MG+1MG/5ML ŞURUP, 100 ML SISE, BENICAL 10 MG+20MG+2MG/5 ML SURUP, 100 MLCategories: Alpha-and Beta-adrenergic Agonists, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  5. Drug

    Methylphenidate

    go.drugbank.com/drugs/DB00422
    ApprovedInvestigational

    for children, adolescents, and adults as recommended by CADDRA (Canadian ADHD Resource Alliance). … Biphentin was designed to be an alternative to separate doses of immediate-release (IR) methylphenidate by providing a biphasic concentration-time profile when given as a single dose.

    Categories: Methylphenidate and isomer, Respiratory and CNS StimulantsProducts: METHYLPHENIDAT-HCL NX 27MG, METHYLPHENIDAT-HCL NX 18MG
  6. Drug

    Isosorbide dinitrate

    go.drugbank.com/drugs/DB00883
    ApprovedInvestigational

    Its actions are similar to nitroglycerin but with a slower onset of action.

    Mixtures: Isosorbide dinitrate and hydralazine hydrochloride, Isosorbide Dinitrate and Hydralazine HydrochlorideCategories: Nitrates and Nitrites, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use
  7. Drug

    Loperamide

    go.drugbank.com/drugs/DB00836
    ApprovedInvestigational

    [A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss. … Loperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea.[L42785] The drug was first synthesized in 1969 and used medically in 1976.

    Mixtures: Meds on the Go, Anti Diarrheal and Anti GasCategories: Alimentary Tract and Metabolism
  8. Drug

    Tavolixizumab

    go.drugbank.com/drugs/DB15042
    Investigational

    Tavolixizumab is under investigation in clinical trial NCT02318394 (A Phase 1 Study of MEDI0562 in Adult Subjects With Selected Advanced Solid Tumors).

    Synonyms: IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENSTNFRSF4 (TUMOR NECROSIS FACTOR RECEPTOR (TNFR) SUPERFAMILY MEMBER 4, OX40, CD134)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY GAMMA1 HEAVY CHAIN (1-451) (CHIMERIC
  9. Drug

    Flupentixol

    go.drugbank.com/drugs/DB00875
    ApprovedInvestigationalWithdrawn

    It is approved for use in Canada and other countries around the world, but not in the US. … [A229083] Flupentixol is an antagonist of both D1 and D2 dopamine receptors.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: FLUANXOL DEPOT2%10MG/0.5ML, Fluanxol Depot Inj 20mg/ml
  10. Drug

    Furosemide

    go.drugbank.com/drugs/DB00695
    ApprovedInvestigationalVet approved

    [L7961] It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. … Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients.

    Synonyms: 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid, 4-Chloro-N-furfuryl-5-sulfamoylanthranilic acidMixtures: SPIRO COMP RATIO 50MG/20MG, SPIRO COMP RATIO 50MG/20MG