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Displaying results 191 - 200 of 10000 in total
  1. Drug

    Terbinafine

    go.drugbank.com/drugs/DB00857
    ApprovedInvestigationalVet approved

    [A1279] Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues.

    Synonyms: (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine, (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamineProducts: LOSIL-T, ERBITRAX-T
  2. Drug

    Ensulizole

    go.drugbank.com/drugs/DB11115
    Approved

    According to the FDA, the maximal approved concentration of ensulizole is 148 mM although concentrations ranging between 74 and 148mM can be found in commercial sunscreen products [A27151]. … Due to its water solubility, ensulizole is commonly used in products formulated to feel light and less oily [A32259].

    Mixtures: Loreal Paris Skin Expertise Day Moisturizer Futur E Daily Dose Of Pure Vitamin E Normal To Dry Skin SPF 15, To Save Face SPF 30 Plus Facial SunscreenProducts: Dolce and Gabbana The Foundation Perfect Matte Broadspectrum SPF 20 All shades
  3. Drug

    Rifampin

    go.drugbank.com/drugs/DB01045
    ApprovedInvestigational

    [A263768] Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).[A263768]

    Mixtures: PRO TB 4, PRO TB 2Products: TB RIF
  4. Drug

    Octinoxate

    go.drugbank.com/drugs/DB09496
    ApprovedInvestigational

    It is often combined with nanoparticles or other water-resistant liposomes in formulations to increase the localization at the epidermis and decrease the risk of percutaneous absorption. … Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage.

    Mixtures: Studio Look Base de alta cobertura para el rostro con FPS 20 Avena 170-N, Studio Look Base de alta cobertura para el rostro con FPS 20 Avena 170-NProducts: Maybelline New York Dream Wonder Fluid Touch Foundation Broad Spectrum SPF 20 Sunscreen, ESIKA PRO ADVANCE LASTING Long-lasting and comfort SPF 20 (MARRON HAVANA) - BROWN
  5. Drug

    Isopropyl alcohol

    go.drugbank.com/drugs/DB02325
    ApprovedInvestigational

    It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.

    Mixtures: The New Parent First Aid, CVS Health Healing on the Go KitProducts: Antibac on the go, The Green Scissor
  6. Drug

    Melaleuca alternifolia leaf

    go.drugbank.com/drugs/DB14372
    Investigational

    Melaleuca alternifolia leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: I Dew Care Tea Tree O StarterkitSynonyms: Tea Tree, Narrow-leaved Ti-tree Leaf
  7. Drug

    Povidone-iodine

    go.drugbank.com/drugs/DB06812
    ApprovedInvestigational

    Human clinical trials showed the product to be superior to other iodine formulations. Povidone-iodine was immediately marketed, and has since become the universally preferred iodine antiseptic. … During in vitro testing to demonstrate anti-bacterial activity it was found that the complex was less toxic in mice than tincture of iodine.

    Products: TM Titus Medical Povidone Iodine, TM TITUS MEDICAL ANTISEPTIC Non Sterile
  8. Drug

    Trazodone

    go.drugbank.com/drugs/DB00656
    ApprovedInvestigational

    receptor inhibitor (SNRIs) in the treatment of depression. … Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Adrenergic alpha-1 Receptor AntagonistsProducts: Raldesy Tm
  9. Drug

    Veligrotug

    go.drugbank.com/drugs/DB18976
    Approved

    Veligrotug is a humanized IgG1 monoclonal antibody that binds the insulin-like growth factor-1 receptor and blocks ligand-induced receptor autophosphorylation, interrupting IGF-1R signaling. … [L63929] The FDA approved veligrotug-vvze on June 26, 2026, for the treatment of thyroid eye disease regardless of disease activity or duration.[L63798,L63929]

    Synonyms: Immunoglobulin G1, anti-(human insulin-like growth factor I receptor) (human-Mus musculus monoclonal VRDN-001 γ1-chain), disulfide with human-Mus musculus monoclonal VRDN-001 κ-chain, dimer, Immunoglobulin G1-kappa, anti-[Homo sapiens IGF1R (insulin-like growth factor 1 receptor, IGF1-R, IGF-1R, CD221)], chimeric monoclonal antibody (gamma1 heavy chain chimeric (1-454) [VH (Mus musculus IGHV1S81Categories: Insulin-like Growth Factor-1 Receptor Inhibitor
  10. Drug

    Bismuth subsalicylate

    go.drugbank.com/drugs/DB01294
    ApprovedVet approved

    [A230728] It is an active ingredient found in Pepto-Bismol, a common over-the-counter medication that is used to temporarily treat discomforts of the stomach and gastrointestinal tract. … [A230728, A230773] Bismuth subsalicylate was first approved by the FDA in 1939 and is now mainly used to relieve nausea, diarrhea, and gastrointestinal discomfort.

    Mixtures: Pepto-Bismol and Pepto-Bismol To Go, Pepto-Bismol and Pepto-Bismol To GoProducts: Pepto-Bismol To Go, Medi-First Pep-T-Med