Search
Methylchloroisothiazolinone
go.drugbank.com/drugs/DB14197ApprovedIt is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness, and moderate to severe swelling in the eye area. … It is found within many commercially available cosmetics, lotions, and makeup removers.
Synonyms: 4-Isothiazolin-3-one, 5-chloro-2-methyl-, 5-Chloro-N-methylisothiazolin-3-oneCategories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingEszopiclone
go.drugbank.com/drugs/DB00402ApprovedInvestigationalThis sets it apart from many other hypnotic sedatives, which are generally approved only for the relief of short-term (6-8 weeks) insomnia. Eszopiclone was initially approved by the FDA in 2004. … It is the active stereoisomer of zopiclone, belonging to the class of drugs known as _cyclopyrrolones_.
Synonyms: (+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine-1-carboxylate, (+)-(5S)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl-4-methylpiperazine-1-carboxylateCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesIndomethacin
go.drugbank.com/drugs/DB00328ApprovedInvestigationalNSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole … -3-acetic acid.
Mixtures: INDOBIOTIC GOZ DAMLASI, 5 MLCategories: P-glycoprotein inhibitors, P-glycoprotein substratesTribromsalan
go.drugbank.com/drugs/DB20138ApprovedWithdrawnTribromsalan is a small molecule drug. Tribromsalan has a monoisotopic molecular weight of 446.81 Da.
Synonyms: 3,4',5-tribromosalicylanilideEthotoin
go.drugbank.com/drugs/DB00754ApprovedEthotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression.
Synonyms: 1-ethyl-2,5-dioxo-4-phenylimidazolidine, (±)-3-ethyl-5-phenylhydantoinCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A InducersEtoricoxib
go.drugbank.com/drugs/DB01628ApprovedInvestigationalWithdrawnIt is approved in more than 60 countries worldwide but not in the US. … Etoricoxib is a new COX-2 selective inhibitor.
Categories: Heterocyclic Compounds, 1-Ring, COX-2 InhibitorsSynonyms: 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine, 5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinylGlyburide
go.drugbank.com/drugs/DB01016ApprovedInvestigational[A183617] Glyburide was granted FDA approval on 1 May 1984.[L8117] A formulation with metformin was granted FDA approval on on 31 July 2000.[L8120] … [L8123] It is typically given to patients who cannot be managed with the standard first line therapy, [metformin].
Synonyms: 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea, 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylureaMixtures: DUPLAX 500 MG/5 MG FILM KAPLI TABLET, 120 ADET, DUPLAX 500 MG/5 MG FILM KAPLI TABLET, 180 ADETPalbociclib
go.drugbank.com/drugs/DB09073ApprovedInvestigationalIt is a second generation cyclin-dependent kinase inhibitor[A176798] selected from a group of pyridopyrimidine compounds due to its favorable physical and pharmaceutical properties. … Palbociclib is a piperazine pyridopyrimidine[A176792] that acts in the cell cycle machinery.
Synonyms: 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-8h-pyrido(2,3-d)pyrimidin-7-one, 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-oneMixtures: REAMPLA®, REAMPLA®Diflunisal
go.drugbank.com/drugs/DB00861ApprovedDiflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs.
Categories: Non COX-2 selective NSAIDSSynonyms: 2-(hydroxy)-5-(2,4-difluorophenyl)benzoic acid, 5-(2,4-difluorophenyl)salicylic acid5-deoxyflavanone
go.drugbank.com/drugs/DB03601ExperimentalThese are compounds containing a flavan-3-one moiety, whose structure is characterized by a 2-phenyl-3,4-dihydro-2H-1-benzopyran bearing a ketone at the carbon C3. … 5-deoxyflavanone is a solid. This compound belongs to the flavanones.
Synonyms: 5-deoxyflavanone