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Displaying results 191 - 200 of 10000 in total
  1. Drug

    Xaluritamig

    go.drugbank.com/drugs/DB18137
    Investigational

    Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.

    Synonyms: immunoglobulin G1-scFv-CH/G1-kappa, anti-[Homo sapiens STEAP1 (STEAP family member 1, six transmembrane epithelial antigen of the prostate 1, STEAP1 metalloreductase) and anti-[Homo sapiens CD3, bispecific
  2. Drug

    Racepinephrine

    go.drugbank.com/drugs/DB11124
    Approved

    Racepinephrine is a racemic mixture consisting of d-[DB00668] and l-[DB00668] enantiomers. Epinephrine is a non-selective α- and β-adrenergic receptor agonist. … It is an active ingredient in oral inhalation over-the-counter products as racepinephrine hydrochloride.

    Mixtures: Gingicord W Epineph and Alum Size No 1, Gingicord W Epineph and Alum Size No 3Categories: Epinephrine and similars, Alpha-and Beta-adrenergic Agonists
  3. Drug

    Loperamide

    go.drugbank.com/drugs/DB00836
    ApprovedInvestigational

    [A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss. … Loperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea.[L42785] The drug was first synthesized in 1969 and used medically in 1976.

    Mixtures: Meds on the Go, Anti Diarrheal and Anti GasCategories: Alimentary Tract and Metabolism
  4. Drug

    Methylphenidate

    go.drugbank.com/drugs/DB00422
    ApprovedInvestigational

    for children, adolescents, and adults as recommended by CADDRA (Canadian ADHD Resource Alliance). … Biphentin was designed to be an alternative to separate doses of immediate-release (IR) methylphenidate by providing a biphasic concentration-time profile when given as a single dose.

    Categories: Methylphenidate and isomer, Respiratory and CNS StimulantsProducts: METHYLPHENIDAT-HCL NX 27MG, METHYLPHENIDAT-HCL NX 18MG
  5. Drug

    Pseudoephedrine

    go.drugbank.com/drugs/DB00852
    Approved

    Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system. … [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889.

    Mixtures: IBUCOLD PLUS 100MG+15MG+1MG/5ML ŞURUP, 100 ML SISE, BENICAL 10 MG+20MG+2MG/5 ML SURUP, 100 MLCategories: Alpha-and Beta-adrenergic Agonists, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  6. Drug

    Isosorbide dinitrate

    go.drugbank.com/drugs/DB00883
    ApprovedInvestigational

    Its actions are similar to nitroglycerin but with a slower onset of action.

    Mixtures: Isosorbide dinitrate and hydralazine hydrochloride, Isosorbide Dinitrate and Hydralazine HydrochlorideCategories: Nitrates and Nitrites, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use
  7. Drug

    Nitrofurantoin

    go.drugbank.com/drugs/DB00698
    ApprovedInvestigationalVet approved

    [L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. … [A179824] This drug is more resistant to the development of bacterial resistance because it acts on many targets at once.

    Synonyms: N-(5-Nitrofurfurylidene)-1-aminohydantoinProducts: Macrodantin Cap 25mg, Novo-furan Sus 25mg/5ml
  8. Drug

    Tavolixizumab

    go.drugbank.com/drugs/DB15042
    Investigational

    Tavolixizumab is under investigation in clinical trial NCT02318394 (A Phase 1 Study of MEDI0562 in Adult Subjects With Selected Advanced Solid Tumors).

    Synonyms: IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENSTNFRSF4 (TUMOR NECROSIS FACTOR RECEPTOR (TNFR) SUPERFAMILY MEMBER 4, OX40, CD134)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY GAMMA1 HEAVY CHAIN (1-451) (CHIMERIC
  9. Drug

    Flupentixol

    go.drugbank.com/drugs/DB00875
    ApprovedInvestigationalWithdrawn

    It is approved for use in Canada and other countries around the world, but not in the US. … [A229083] Flupentixol is an antagonist of both D1 and D2 dopamine receptors.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: FLUANXOL DEPOT2%10MG/0.5ML, Fluanxol Depot Inj 20mg/ml
  10. Drug

    Epirubicin

    go.drugbank.com/drugs/DB00445
    ApprovedInvestigational

    An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.

    Categories: Anthracyclines and Related Substances, Antineoplastic and Immunomodulating AgentsProducts: PHARMORUBICIN CS 20MG/10ML, PHARMORUBICIN CS 50MG/25ML