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Displaying results 191 - 200 of 10000 in total
  1. Drug

    Ceftazidime

    go.drugbank.com/drugs/DB00438
    ApprovedInvestigational

    [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone or in combination with the non-β-lactam β-lactamase inhibitor [avibactam] to treat a variety of … [A232920] β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately

    Mixtures: CEFAZIME FOR INJECTION 1 g/vialCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  2. Drug

    Tocilizumab

    go.drugbank.com/drugs/DB06273
    ApprovedInvestigational

    [L43697] After being investigated to treat severely ill patients with COVID-19,[A193278,L12837,L12843] tocilizumab was approved by the European Commission in December 2021 to treat COVID-19 in adults receiving … systemic corticosteroids and supplemental oxygen or mechanical ventilation.

    Categories: Biologics for Rheumatoid Arthritis Treatment, Experimental Unapproved Treatments for COVID-19Products: ACTEMRA (162 MG SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE), ACTEMRA 162MG/0.9ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE
  3. Drug

    Vancomycin

    go.drugbank.com/drugs/DB00512
    ApprovedInvestigational

    Such an oral liquid formulation is expected to make _Clostridium difficile_ associated diarrhea therapy more accessible in comparison to previously available specialty compounding products [LP1196]. … As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and enterocolitis

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Vancomycin Injection USP In 5% Dextrose, Vancomycin Injection USP In 0.9% Sodium Chloride
  4. Drug

    Asparaginase Escherichia coli

    go.drugbank.com/drugs/DB00023
    ApprovedInvestigational

    For patients who develop hypersensitivity to _E. coli_-derived formulations of L-asparaginase, the use of PEGylated or non-PEGylated [DB08886] is recommended [A31999]. … It also facilitates the production of oxaloacetate which is needed for general cellular metabolism.

    Synonyms: Asparaginase IIProducts: LEUNASE FOR INJECTION 10,000 iu/vial, KIDROLASE 10000 UI
  5. Drug

    Artemisia californica pollen

    go.drugbank.com/drugs/DB10909
    Approved

    Artemisia californica pollen is the pollen of the Artemisia californica plant. Artemisia californica pollen is mainly used in allergenic testing.

    Synonyms: coast sage pollen extractMixtures: Number Four Weed Mixture
  6. Drug

    Paliperidone

    go.drugbank.com/drugs/DB01267
    ApprovedInvestigational

    Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006. … Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: INVEGA Sustenna Prolonged Release Suspension for IM Injection 25mg/0.25 ml, INVEGA Sustenna Prolonged Release Suspension for IM Injection 50mg/0.5 ml
  7. Drug

    Carbetocin

    go.drugbank.com/drugs/DB01282
    ApprovedInvestigational

    It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus. … Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth.

    Synonyms: deamino-2-O-methyltyrosine-1-carbaoxytocin, 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocinProducts: DURATOCIN RTS SOLUTION FOR INJECTION 100 MCG/ML, Pharmidea Carbetocin 100 microgram/ml solution for injection
  8. Drug

    Ofatumumab

    go.drugbank.com/drugs/DB06650
    ApprovedInvestigational

    [L12753] The FDA subsequently approved ofatumumab for the treatment of RMS on August 20, 2020. … In February 2020, FDA and EMA approved Supplemental Biologics License Application (sBLA) and Marketing Authorization Application (MAA), respectively, for ofatumumab for the treatment of RMS in adults.

    Products: KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MG/0.4ML, Bonspri 20mg/0.4mL Solution for Injection in Pre-filled syringe
  9. Drug

    Pemetrexed

    go.drugbank.com/drugs/DB00642
    ApprovedInvestigational

    It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative … Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.[A253907]

    Products: PEMIREX FOR INJ. 100 MG, PEMIREX FOR INJ. 500 MG
  10. Drug

    Insulin glulisine

    go.drugbank.com/drugs/DB01309
    Approved

    If left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening … cells that the body is no longer able to produce insulin on its own.

    Categories: Drugs Used in Diabetes, Insulins and Analogues for Injection, Fast-ActingProducts: APIDRA 100 U/ML- SOLUTION FOR INJECTION IN VIAL, APIDRA 100 Units/ml Solution for Injection in vial