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Terconazole
go.drugbank.com/drugs/DB00251Approved[A178093]Due to the existence of 2 stereocentres, there are 4 possible stereoisomers for terconazole. … Terconazole is an anti-fungal drug that is mainly used to treat vaginal yeast infections (or vaginal candidiasis). It is classified as a _triazole ketal derivative_.
Products: FUNGISTAT OVULOS DE 80 MG.Reproxalap
go.drugbank.com/drugs/DB16688InvestigationalReproxalap (previously ADX 102 or NS-2) is a small molecule inhibitor being developed by Aldeyra Therapeutics investigated against dry eye disease, allergic conjunctivitis, noninfectious anterior uveitis … [L32990] NS-2 has orphan drug status due to it being investigated for treatment of Sjogren-Larsson syndrome.[L32990]
Categories: Heterocyclic Compounds, 2-RingSynonyms: ADX 102, ALD-102Butenafine
go.drugbank.com/drugs/DB01091ApprovedIn particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes.
Synonyms: (4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine, N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamineProducts: BUTAFLY % 1 LOSYON ,10 ML, BUTEFIN %1 KREM, 30 GGatifloxacin
go.drugbank.com/drugs/DB01044ApprovedInvestigationalWithdrawnIt was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV.
Categories: Heterocyclic Compounds, 2-Ring, 4-QuinolonesSynonyms: 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid, 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acidDichloroacetic acid
go.drugbank.com/drugs/DB08809ApprovedInvestigationalWithdrawnA phase 1 study in 5 patients concluded that DCA was safe, but wasn't designed to establish effectiveness. … Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three hydrogen atoms of the methyl group have been replaced by chlorine atoms.
Products: Bichloracetic Acid 100%DTX-101
go.drugbank.com/drugs/DB17699InvestigationalDTX-101 is an investigational gene therapy consisting of an adeno-associated virus serotype Rh10 vector encoding the human Factor Ix gene. … It was previously investigated for the treatment of hemophilia B; however, the clinical development of DTX-101 was discontinued.[L46103]
Synonyms: DTX 101Efgartigimod alfa
go.drugbank.com/drugs/DB15270ApprovedInvestigational[A243759,A243784] Efgartigimod alfa is a first-in-class[L39501] antagonist of the neonatal Fc receptor (FcRn) used in the treatment of MG. … Myasthenia gravis (MG) is an autoimmune disorder characterized by significant muscle weakness - particularly in the eye, throat, and extremities - caused by autoantibodies attacking the neuromuscular junction
Categories: Human Immunoglobulin GFimasartan
go.drugbank.com/drugs/DB09279InvestigationalIt has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. … Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure.
Categories: Agents Acting on the Renin-Angiotensin SystemProducts: KANARB®PLUS FILM COATED TABLETS 120 MG/12.5 MG, KANARB®PLUS FILM COATED TABLETS 60 MG/12.5 MGPrulifloxacin
go.drugbank.com/drugs/DB11892InvestigationalPrulifloxacin has been investigated for the treatment of Urinary Tract Infection.
Categories: Heterocyclic Compounds, 2-Ring, 4-QuinolonesProducts: Unidrox 600 mg Filmtabletten, DARFLOX TABLETS 100Propolis wax
go.drugbank.com/drugs/DB11355ApprovedInvestigationalIt is often found in topical formulations used to soothe minor skin irritations.
Mixtures: Propolis 50 Volume Mist, Medi SM 24K Gold Hydrogel Peptide Mask PackProducts: Ramosu Propolis Extract 100