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Amiloride
go.drugbank.com/drugs/DB00594ApprovedInvestigationalA pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and c...
Mixtures: PLENACOR D, Nu-amilzide 5/50 Mg TabErgotamine
go.drugbank.com/drugs/DB00696ApprovedA vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Mixtures: DEGORKAF-DUOAngelica sinensis root
go.drugbank.com/drugs/DB14336InvestigationalAngelica sinensis root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: Blood Care Honzo Seika Chinese Herbal Aroma Oil, Blood Care Honzo Seika Chinese Herbal Aroma OilProducts: Breast Care Honzo Seika Chinese Herbal Aroma OilCorynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10584ApprovedInvestigationalMixtures: Dt Polio Adsorbed - Sus Im, Bio Farma Adsorbed DT VaccineTonapofylline
go.drugbank.com/drugs/DB12569InvestigationalTonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and Congestive Heart Failure.
Guanoxan
go.drugbank.com/drugs/DB13211ApprovedGuanoxan was approved in the UK but was withdrawn from the market due to hepatotoxicity.
Clobutinol
go.drugbank.com/drugs/DB09004ApprovedWithdrawnClobutinol is a cough suppressant that is withdrawn from the US and EU markets. Clobutinol may prolong the QT interval. In 2007, Clobutinol was determined to cause cardiac arrhythmia in some patients.
Brexanolone
go.drugbank.com/drugs/DB11859ApprovedInvestigationalsusceptible to PPD whereas many commonly used anti-depressive medications elicit actions that may modulate the presence and activity of substances like serotonin, norepinephrine, and/or monoamine oxidase but do
Atibuclimab
go.drugbank.com/drugs/DB06546InvestigationalAtibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis.
Buformin
go.drugbank.com/drugs/DB04830ApprovedWithdrawnIt was withdrawn from the market in most countries due to a high risk of causing lactic acidosis.