Search
Benzimate
go.drugbank.com/drugs/DB05170ExperimentalIt is currently under investigation by AmpliMed and is in phase I of clinical trial. … Benzimate is the lead compound selected from a series of compounds known as benzimidazoles.
Tropisetron
go.drugbank.com/drugs/DB11699ApprovedInvestigationalWithdrawnAs a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting … Tropisetron is an indole derivative with antiemetic activity.
Misoprostol
go.drugbank.com/drugs/DB00929ApprovedInvestigational[L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the … Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions.
Mixtures: DICLOENAC SODIUM and MISOPROSTOL DR, Diclofenac sodium and Misoprostol DREugenol
go.drugbank.com/drugs/DB09086ApprovedInvestigationalIt has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain control. … Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves.
Categories: Compounds used in a research, industrial, or household settingLonafarnib
go.drugbank.com/drugs/DB06448ApprovedInvestigationalaberrant farnesylated form of lamin A called progerin in the inner nuclear membrane. … Hutchinson-Gilford progeria syndrome (HGPS) is a rare autosomal dominant disorder estimated to affect approximately one in 20 million individuals resulting in adverse symptoms associated with premature
Carbopol 974P
go.drugbank.com/drugs/DB05384ApprovedWithdrawnCarbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of pathogens. … It was under development by ReProtect LLC. It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies.
Categories: Compounds used in a research, industrial, or household settingBictegravir
go.drugbank.com/drugs/DB11799ApprovedInvestigationalIt has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.[L43677] … Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection.
Categories: Antivirals used in combination for the treatment of HIV infectionsAliskiren
go.drugbank.com/drugs/DB09026ApprovedInvestigationalAliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension. … [A203624] It was developed by Speedel and Novartis and initially approved by the FDA in early 2007.
Categories: Agents Acting on the Renin-Angiotensin SystemInsulin icodec
go.drugbank.com/drugs/DB16693ApprovedInvestigationalIt is a re-engineered version of the ultra long-acting oral basal insulin OI338, with several modifications introduced to significantly extend the half-life. … [A264093] These modifications - which cause increased serum albumin binding and attenuated insulin receptor affinity - result in a mean half-life of approximately 196 hours, allowing for once-weekly administration
Categories: Drugs Used in DiabetesIvermectin
go.drugbank.com/drugs/DB00602ApprovedInvestigationalVet approved[L31453] Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A<sub>1a</sub> (22,23-dihydroavermectin B<sub>1a</sub>) and 10% 5-O-demethyl-25-de … Applied topically, it may be used in the treatment of head lice infestation.
Categories: Compounds used in a research, industrial, or household settingProducts: I-Dectin 0.5 % Pour-On, I-Dectin 0.4% w/v Oral Solution