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Oxytocin
go.drugbank.com/drugs/DB00107ApprovedInvestigationalVet approved[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent du Vigneaud; he was later recognized with a Nobel prize for his work. … [A229013] Oxytocin also serves a role in metabolic homeostasis and cardiovascular regulation.[A228593,A229098]
Estradiol acetate
go.drugbank.com/drugs/DB13952ApprovedVet approvedEstradiol acetate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously within the human body. … , estrone and estriol at the receptor level.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A1 SubstratesMecobalamin
go.drugbank.com/drugs/DB03614ApprovedInvestigationalMixtures: Protect Cardio AF, Folika-VSincalide
go.drugbank.com/drugs/DB09142ApprovedIt is identified as the 8-amino acid C-terminal segment of cholecystokinin and is also known as _CCK-8_. … Sincalide is a medication given by injection to assist in the diagnosis of gallbladder and pancreas disorders.
Daridorexant
go.drugbank.com/drugs/DB15031ApprovedInvestigationalDaridorexant, formerly known as nemorexant, is a selective dual orexin receptor antagonist used to treat insomnia. … It chronically affects the person's daily functioning and long-term health effects, as insomnia is often associated with comorbidities such as hypertension, diabetes, and depression.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesLucinactant
go.drugbank.com/drugs/DB04897ApprovedIt contains sinapultide, a novel, hydrophobic, 21-amino acid peptide (leucine and lysine repeating units, KL4 peptide) designed to mimic human surfactant protein-B (SB-P). … Lucinactant is a new synthetic peptide-containing surfactant for intratracheal use.
Beeswax
go.drugbank.com/drugs/DB11600ApprovedIt is also used as a coating in the manufacture of modified-release oral preparations … Beeswax is used as a stiffening agent in ointments and creams, and enables water to be incorporated to produce water-in-oil emulsions.
Bacampicillin
go.drugbank.com/drugs/DB01602ApprovedWithdrawnIt is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of cell wall mucopeptides. … Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration.
Vamorolone
go.drugbank.com/drugs/DB15114ApprovedInvestigational[L48676] Vamorolone is positioned as having a more tolerable adverse effect profile than other corticosteroids owing to its unique receptor binding profile,[A261976] thus providing an additional treatment … Vamorolone is a novel and fully synthetic glucocorticoid developed by Santhera Pharmaceuticals.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersAmmonia
go.drugbank.com/drugs/DB11118ApprovedInvestigationalAlthough ammonia is used as a food additive in the anhydrous form and serves as a starting material in pharmaceutical and commercial products, it is caustic and hazardous when concentrated. … It is a colorless gas with a pungent smell, and become NH4, or ammonium ion, when in water.