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Abacavir
go.drugbank.com/drugs/DB01048ApprovedInvestigationalIn vivo, abacavir sulfate dissociates to its free base, abacavir. … Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring.
Mixtures: N/ACategories: Antivirals used in combination for the treatment of HIV infections, Antivirals for Systemic UseUnexpanded umbilical cord-derived allogeneic CD34- hematopoietic stem cells
go.drugbank.com/drugs/DB28348Approvedin adult patients for whom a suitable donor is not available. … [L54106] Zemcelpro also contains [dorocubicel], a preparation CD34+ HSCs derived from the same cord blood sample and expanded _ex vivo_ using [UM-171].
Darunavir
go.drugbank.com/drugs/DB01264ApprovedInvestigational[L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19, due to in vitro evidence supporting its ability to combat this infection. … [L9227] As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006.
Mixtures: VIRONTAR N COMPRIMIDOS RECUBIERTOS, VIRONTAR N COMPRIMIDOS RECUBIERTOSCategories: Antivirals used in combination for the treatment of HIV infections, Antivirals for Systemic UseTemazepam
go.drugbank.com/drugs/DB00231ApprovedIn particular, before temazepam saw regular prescription use in civilians it was - and still is - employed by the US military as a sedative-hypnotic medication to be taken by soldiers, pilots, etc. to … and approved later on.
Products: Co Temazepam Capsules 15mg, Co Temazepam Capsules 30mgAnagrelide
go.drugbank.com/drugs/DB00261ApprovedInvestigational[L14153] It is an oral imidazoquinazoline that was first approved for use in the US in 1997.[A214274] It appears to carry a better response rate than other thrombocythemia treatments (e.g. … Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms.
Pegloticase
go.drugbank.com/drugs/DB09208ApprovedInvestigationalPegloticase is a porcine recombinant PEGylated uricase indicated for the treatment of chronic gout in adult patients that do not respond to other types of therapies. … [L42425] Pegloticase was approved by the FDA in 2014, and in 2022, the drug label included the co-administration of pegloticase and methotrexate.[L42425]
Categories: Compounds used in a research, industrial, or household settingElacestrant
go.drugbank.com/drugs/DB06374ApprovedInvestigational[A256838,L44918] In January 2023, it was approved by the FDA for the treatment of ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer. … [L44918,L44948] It received a similar approval in the EU in September 2023.
Categories: Estrogens, Non-SteroidalGastric intrinsic factor
go.drugbank.com/drugs/DB09349ApprovedIntrinsic factor is not currently available in any FDA or Health Canada approved products. … on in the small intestine.
Mixtures: EnLyte Extra-LNDL-dimyristoylphosphatidylglycerol
go.drugbank.com/drugs/DB11284ApprovedDL-dimyristoylphosphatidylglycerol is a phospholipid used in commercially available pharmaceutical preparations to solubilize drugs for injection.
Avatrombopag
go.drugbank.com/drugs/DB11995ApprovedInvestigational[L2931] It is administered orally as the salt form avatrombopag maleate. … [F95] Avatrombopag was first approved by the FDA in May 2018 for use in adults with chronic liver disease who are scheduled to undergo a procedure.