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Displaying results 2011 - 2020 of 4646 in total
  1. Drug

    Adagrasib

    go.drugbank.com/drugs/DB15568
    ApprovedInvestigational

    KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations. … [L44361,L44366] Adagrasib joins [sotorasib] as another KRAS<sup>G12C</sup> inhibitor approved by the FDA.[A254062]

    Synonyms: ((2s)-4-(7-(8-chloronaphthalen-1-yl)-2-(((2s)-1- methylpyrrolidin-2-yl)methoxy)-5,6,7,8- tetrahydropyrido(3,4-d)pyrimidin-4-yl)-1-(2-fluoroprop2-enoyl)piperazin-2-yl)acetonitrile, 2-piperazineacetonitrile, 4-(7-(8-chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-(((2s)-1-methyl-2-pyrrolidinyl)methoxy)pyrido(3,4-d)pyrimidin-4-yl)-1-(2-fluoro-1-oxo-2-propen-1-yl)-, (2s)-
  2. Drug

    Nebicapone

    go.drugbank.com/drugs/DB14849
    Investigational

    of Levodopa/Benserazide 200/50 mg Plus a Single-dose of Nebicapone 150 mg). … Nebicapone is under investigation in clinical trial NCT03097211 (Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose

  3. Drug

    Mirvetuximab soravtansine

    go.drugbank.com/drugs/DB12489
    ApprovedInvestigational

    Mirvetuximab soravtansine-gynx (IMGN853) is an antibody-drug conjugate (ADC) formed by a monoclonal antibody (M9346A) that targets folate receptor alpha (FRα), covalently joined by a cleavable disulfide linker to the genotoxic compound D...

  4. Drug

    Piperonyl butoxide

    go.drugbank.com/drugs/DB09350
    ApprovedVet approved

    Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is used for the treatment of head, pubic (crab), and body lice. Piperonyl butoxide is a synergist. It has no pesticidal activity of its own...

    Mixtures: Weeks and Leo Complete Lice Treatment, Lice MD Complete
  5. Drug

    Levorphanol

    go.drugbank.com/drugs/DB00854
    Approved

    A narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.

  6. Drug

    Sulisobenzone

    go.drugbank.com/drugs/DB11185
    Approved

    Benzophenones may be found organically in fruits such as grapes [L2669]. … As a group, benzophenones may be used to delay photodegradation or extend shelf life in toiletries and plastic surface coatings [L2671].

    Synonyms: 2-benzoyl-5-methoxy-1-phenol-4-sulfonic acid, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acidInternational brands: Uvasorb S 5, MS 40
  7. Drug

    Triflupromazine

    go.drugbank.com/drugs/DB00508
    ApprovedVet approved

    A phenothiazine used as an antipsychotic agent and as an antiemetic.

    Categories: Serotonin 5-HT2 Receptor Antagonists
  8. Drug

    Cedazuridine

    go.drugbank.com/drugs/DB15694
    ApprovedInvestigational

    [A215107, A215112, A215117, A215127, L14897] Cedazuridine was first reported in 2014,[A215107] and was subsequently approved by the FDA on July 7, 2020, in combination with [decitabine] for sale by

  9. Drug

    Silver nitrate

    go.drugbank.com/drugs/DB11080
    Approved

    Silver nitrate is an inorganic compound with the chemical formula AgNO3. In its solid form, silver nitrate is coordinated in a trigonal planar arrangement. It is often used as a precursor to other silver-containing compounds. It is used ...

    Synonyms: Nitrato de plataMixtures: Grafco Silver Nitrate (75% Silver Nitrate, 25% Potassium Nitrate), Grafco Applicator 45 Cm
  10. Drug

    Foscenvivint

    go.drugbank.com/drugs/DB15034
    Investigational

    PRI-724 is under investigation in clinical trial NCT03620474 (Safety and Effectiveness of PRI-724 for Hepatitis C or B Virus Derived Liver Cirrhosis).