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Fusidic acid
go.drugbank.com/drugs/DB02703ApprovedInvestigationalAn antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in sys...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsNitrilotriacetic acid
go.drugbank.com/drugs/DB03040ExperimentalNitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.)
Sphingosine
go.drugbank.com/drugs/DB03203InvestigationalAn amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)
Categories: P-glycoprotein substratesFlavin mononucleotide
go.drugbank.com/drugs/DB03247ApprovedInvestigationalFlavin mononucleotide (FMN), also known as riboflavin 5'-phosphate, is one of the two major coenzymes derived from riboflavin (vitamin B2) and is one of the principal forms in which dietary riboflavin is found. FMN is composed of an isoa...
Mixtures: Soluvit N, Soluvit NMobocertinib
go.drugbank.com/drugs/DB16390ApprovedInvestigationalWithdrawnMobocertinib is a kinase inhibitor targeted against human epidermal growth factor receptor (EGFR). It is used specifically in the treatment of non-small cell lung cancer (NSCLC) caused by exon 20 insertion mutations in the EGFR gene, whi...
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsNaringin
go.drugbank.com/drugs/DB16859ExperimentalCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsCrinecerfont
go.drugbank.com/drugs/DB18518ApprovedInvestigationalPatients with congenital adrenal hyperplasia (CAH) face two major problems: adrenal insufficiency, caused by insufficient endogenous cortisol production, and androgen excess, caused by a counter-regulatory overproduction of adrenocortico...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesImlunestrant
go.drugbank.com/drugs/DB19043ApprovedInvestigationalImlunestrant is a brain-penetrant selective estrogen receptor antagonist and degrader. The FDA approved imlunestrant on September 25, 2025 as a treatment for estrogen receptor (ER)-positive, HER2-negative, estrogen receptor 1 (ESR1)-muta...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesBenzgalantamine
go.drugbank.com/drugs/DB19353ApprovedInvestigationalBenzgalantamine is a prodrug of galantamine. Gastrointestinal adverse effects are the most frequently reported side effects in patients undergoing treatment with cholinesterase inhibitors, including galantamine, and are often a reason fo...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates