Search
Crofelemer
go.drugbank.com/drugs/DB04941ApprovedInvestigationalCrofelemer, previously known as the investigational drug SP-303, is a novel proanthocyanidin purified from the bark latex of the Amazonian Croton tree <i>Croton lechleri</i>. … It is marketed under the brand name Fulyzaq and indicated for the symptomatic treatment of non-infectious diarrhea in adult patients with HIV/AIDS who are taking antiretroviral therapy.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingFerric oxide
go.drugbank.com/drugs/DB11576ApprovedInvestigationalIt is one of the three main oxides of iron, the other two being iron(II) oxide (FeO) the rarer form, and iron(II,III) oxide (Fe3O4) which naturally as magnetite. … Iron(III) oxide or ferric oxide is the inorganic compound with the formula Fe2O3.
Mixtures: Cellzyme ON-TOX, Cellzyme ON-TOXCategories: Compounds used in a research, industrial, or household settingSofosbuvir
go.drugbank.com/drugs/DB08934ApprovedInvestigationalIn a joint recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) recommend Sofosbuvir as first line therapy … Both Canadian and American guidelines list Epclusa as a first line recommendation for all genotypes of HCV [L852, A19626].
Mixtures: HARVONI®, EPCLUSA®Categories: P-glycoprotein substrates, Treatments for Hepatitis CBoceprevir
go.drugbank.com/drugs/DB08873ApprovedWithdrawnwith [DB00811], [DB00008], and [DB00022] as first line therapy for Hepatitis C [A19593]. … Approved in May 2011 by the FDA, Victrelis is indicated for the treatment of HCV genotype 1 in combination with [DB00811], [DB00008], and [DB00022] [FDA Label].
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: VICTRELIS ® CAPSULAS 200 MG (MOLECULA PROTEGIDA)Succimer
go.drugbank.com/drugs/DB00566ApprovedInvestigationalA mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.
Synonyms: DMS-ACategories: Compounds used in a research, industrial, or household settingLaromustine
go.drugbank.com/drugs/DB05817InvestigationalVNP40101M is a novel alkylating agent that has been used in trials studying the treatment of Leukemia, Lymphoma, Lung Cancer, Small Intestine Cancer, and Myelodysplastic Syndromes, among others.
Categories: Cytochrome P-450 CYP2B6 Inhibitors, Cytochrome P-450 SubstratesLoratadine
go.drugbank.com/drugs/DB00455ApprovedInvestigationalLoratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Mixtures: THERAFLU N 12, SENSIBIT-RINCategories: P-glycoprotein inhibitors, P-glycoprotein substratesXylitol
go.drugbank.com/drugs/DB11195ApprovedInvestigationalIt is widely used as a sugar substitute and in "sugar-free" food products. … Xylitol is a naturally occurring five-carbon sugar alcohol found in most plant material, including many fruits and vegetables. Xylitol-rich plant materials include birch and beechwood [A22081].
Mixtures: Fluor-a-day, Fluor-a-dayCategories: Compounds used in a research, industrial, or household settingMangafodipir
go.drugbank.com/drugs/DB06796ApprovedInvestigationalWithdrawnMangafodipir is a contrast agent used as a diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver and pancreas. … Manganese absorption into the tissues that makes the normal tissue appear brighter in MRI is limited in abnormal or cancerous tissue.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingProducts: TESLASCAN 0,01MMOL 50 ML FLAKON, 1 ADETTosedostat
go.drugbank.com/drugs/DB11781InvestigationalIt has demonstrated anti-tumour activity in a number of models of cancer, both as a single agent and in synergy with cytotoxic agents such as carboplatin and paclitaxel. … It entered the clinical trial in patients with haematological malignancies.