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Syphilis
go.drugbank.com/conditions/DBCOND0014490Synonyms: (Syphilis (& [other and unspecified])) or (treponemal infection)Thrombin alfa
go.drugbank.com/drugs/DB11572ApprovedThrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically converted to a two-chain active form (using a protein derived from snakes) and is purified by a chromatographic … The thrombin alfa product ultimate comes from recombinant human prethrombin-1 [L2079].
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsNedosiran
go.drugbank.com/drugs/DB17635ApprovedInvestigational[A261685] Nedosiran was approved by the FDA on October 2<sup>nd</sup>, 2023, under the brand name RIVFLOZA to lower urinary oxalate levels in children 9 years of age and older and adults with primary … This approval is based on the favorable results from the pivotal phase 2 PHYOX<sup>TM</sup>2 and interim data from the ongoing phase 3 PHYOX<sup>TM</sup>3 clinical trials.[L48325]
Categories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and ProteinsLice Infestations
go.drugbank.com/conditions/DBCOND0000250Synonyms: Pediculosis and other lice, Louse infestation (& [pediculosis and phthirus] or [lice])Oxethazaine
go.drugbank.com/drugs/DB12532ApprovedWithdrawn[A33104] Oxetacaine is approved by Health Canada since 1995 for its use as an antacid combination in over-the-counter preparations. … Its actions have shown to relieve dysphagia, relieve pain due to reflux, chronic gastritis, and duodenal ulcer.
Categories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseUmeclidinium
go.drugbank.com/drugs/DB09076ApprovedInvestigational[A7719] By blocking the M3 muscarinic receptor, umeclidinium inhibits the binding of acetylcholine and thereby opens up the airways by preventing bronchoconstriction. … COPD is a progressive obstructive lung disease characterized by shortness of breath, cough, sputum production, and chronically poor airflow with a forced expiratory volume in 1 second (FEV1) of less than
Mixtures: Umeclidinium and Vilanterol ElliptaCategories: vilanterol and umeclidinium bromide, vilanterol, umeclidinium bromide and fluticasone furoateHuman C1-esterase inhibitor
go.drugbank.com/drugs/DB06404ApprovedInvestigationalThe disease is characterized by acute attacks of painful, and in some cases, fatal swelling of several soft tissues or edema, which may last up to five days when untreated.[L16586, L16606] … [L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a human genetic disorder caused by a shortage of C1 inhibitor activity that results in an overreaction
Categories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsEndocarditis, Subacute Bacterial
go.drugbank.com/conditions/DBCOND0000330Drugs: Procaine benzylpenicillinSynonyms: Acute and subacute endocarditis, unspecifiedrhThrombin
go.drugbank.com/drugs/DB04923ApprovedWithdrawnThe production of recombinant proteins is not dependent on the availability of blood from animals or human donors and can be scaled-up to meet market demand. … ZymoGenetics is developing rhThrombin, a recombinant form of human thrombin that is not derived from animal or human blood, as an aid to controlling bleeding during surgery.
Takayasu Arteritis
go.drugbank.com/conditions/DBCOND0000704Drugs: PrednisoneSynonyms: Sclerosing aortitis AND arteritis, Idiopathic medial aortopathy AND arteriopathy