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Displaying results 2041 - 2050 of 10000 in total
  1. Drug

    Neladalkib

    go.drugbank.com/drugs/DB21712
    Investigational

    Neladalkib is a small molecule drug. The usage of the INN stem '-alkib' in the name indicates that Neladalkib is a ALK (anaplastic lymphoma kinase) inhibitor. Neladalkib is under investigation in clinical trial NCT06765109 (Neladalkib (N...

    Synonyms: an orally bioavailable ALK inhibitor (a macrocyclic compound containing nitrogen heterocycles)
  2. Drug

    Lofexidine

    go.drugbank.com/drugs/DB04948
    ApprovedInvestigational

    [T209] Lofexidine was developed by US Woldmeds LLC and it was approved by the FDA on May 16, 2018.[L2794] … [A33084] It was first studied for use as an antihypertensive in 1980, but its researched was stopped as it was found less effective for the treatment of hypertension than clonidine.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  3. Drug

    Zinc acetate

    go.drugbank.com/drugs/DB14487
    ApprovedInvestigational

    Mixtures: Benadryl Bug Bite Relief, Children's Benadryl Bug Bite ReliefCategories: Alimentary Tract and Metabolism, Various Alimentary Tract and Metabolism Products
  4. Drug

    Andexanet alfa

    go.drugbank.com/drugs/DB14562
    Approved

    It was developed by Portola Pharmaceuticals and was approved in in May 2018. … Andexanet alfa works by binding to Factor Xa inhibitors and prevent them from interacting with endogenous Factor Xa.

    Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and Proteins
  5. Drug

    Isocarboxazid

    go.drugbank.com/drugs/DB01247
    Approved

    [T115] It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription drug on July 1st, 1959. … [A31930] It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders.

    Categories: Monoamine Oxidase Inhibitors, Non-Selective, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  6. Indication

    Post-essential Thrombocythemia Myelofibrosis (Post-ET MF)

    go.drugbank.com/conditions/DBCOND0069581
    Drugs: Ruxolitinib
    Synonyms: Myelofibrosis due to and following essential thrombocythemia, Myelofibrosis due to and following essential thrombocythaemia
  7. Drug

    Fenoprofen

    go.drugbank.com/drugs/DB00573
    Approved

    An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.

    Categories: Antiinflammatory and Antirheumatic Products, Non-Steroids, Antiinflammatory and Antirheumatic Products
  8. Indication

    Diabetic Peripheral Neuropathic Pain (DPN)

    go.drugbank.com/conditions/DBCOND0036250
    Drugs: Duloxetine · Pregabalin · Tapentadol
    Synonyms: Neuropathy co-occurrent and due to diabetes mellitus
  9. Indication

    Cyanide Poisoning

    go.drugbank.com/conditions/DBCOND0053869
    Drugs: Hydroxocobalamin · Nitrous acid · Thiosulfuric acid
    Synonyms: Toxic effect of hydrocyanic acid and cyanides, Cyanides and hydrocyanic acid causing toxic effect
  10. Indication

    Dysbetalipoproteinemia

    go.drugbank.com/conditions/DBCOND0022726
    Drugs: Atorvastatin · Pravastatin · Rosuvastatin
    Synonyms: Familial hyperbetalipoproteinemia and hyperprebetalipoproteinemia, Familial hyperbetalipoproteinaemia and hyperprebetalipoproteinaemia