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Cefepime
go.drugbank.com/drugs/DB01413ApprovedInvestigational[A249050] The popularity of its third-generation predecessors, its clinical efficacy, and the high prevalence of multidrug-resistant bacteria might be some of the factors leading to an increase in the … The activity of cefepime against Enterobacteriaceae, _Pseudomonas aeruginosa_, and _Staphylococcus aureus_ is due to its high stability toward beta-lactamases.
Products: ROXIPIME 2 G IV ENJEKSIYON VE INFÜZYON IÇIN TOZ IÇEREN FLAKON ,1 ADET, ROXIPIME 2 G IV ENJEKSIYON VE INFÜZYON IÇIN TOZ IÇEREN FLAKON ,10 ADETTannic acid
go.drugbank.com/drugs/DB09372ApprovedInvestigationalIt is a type of the commercially available tannins. It acts as a weak acid. … In the old days it was used as antidote against different poisons. Nowadays, tannic acid is applied topically for the treatment of cold sores, diaper rash, fever blisters and poison ivy.
Mixtures: Extrait De FraisesPromethazine
go.drugbank.com/drugs/DB01069ApprovedInvestigational[A189901] Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.
Mixtures: COPHADYL-E COUGH LINCTUSCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Dopamine D2 Receptor AntagonistsThrombin alfa
go.drugbank.com/drugs/DB11572ApprovedThe cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious agents. … The cell culture process used in the manufacture of Thrombin Alfa employs no additives of human or animal origin.
Levomilnacipran
go.drugbank.com/drugs/DB08918ApprovedInvestigational[A261181, A38560] Levomilnacipran is the more active 1S,2R-enantiomer in the racemate [milnacipran]. … [L47946] First approved by the FDA on July 25, 2013, levomilnacipran is used to treat major depressive disorder in adults.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeTromethamine
go.drugbank.com/drugs/DB03754ApprovedInvestigational(From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424) … It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used
Categories: Solutions Affecting the Electrolyte BalanceSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigational[A242372] The topical formulation of sirolimus, marketed as HYFTOR, was approved by the FDA in April 2022: this marks the first topical treatment approved in the US for facial angiofibroma associated with … [A242372] In November 2000, the drug was recognized by the European Agency as an alternative to calcineurin antagonists for maintenance therapy with corticosteroids.
Products: LIKMUN-E, RENACEPTBaclofen
go.drugbank.com/drugs/DB00181ApprovedInvestigationalAlthough originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977.
Categories: GABA-B Receptor AgonistsProducts: BACLENO® 10MG/5ML SOLUCIÓN DE PERFUSIÓNGlucarpidase
go.drugbank.com/drugs/DB08898ApprovedInvestigationalIn 1983, the gene for carboxypeptidase G2, or glucarpidase, was derived from _Pseudomonas_ sp. strain RS-16 to be cloned into _Escherichia coli_, allowing the enzyme to be produced in sufficient quantities … [A7476,A7477] After the discovery of certain bacteria with the capacity to inactivate folate analogs such as methotrexate, carboxypeptidase G was identified and Carboxypeptidase G1 was first isolated
Polaprezinc
go.drugbank.com/drugs/DB09221InvestigationalIt is a zinc-related medicine approved for the first time in Japan, which has been clinically used to treat gastric ulcers [L1307, L1308]. … It was determined that polaprezinc may be effective in pressure ulcer treatment [A31856].