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Trovafloxacin
go.drugbank.com/drugs/DB00685ApprovedWithdrawnTrovafloxacin is a broad spectrum antibiotic that has been commonly marketed under the brand name Trovan by Pfizer. … It exerts its antibacterial activity by inhibiting the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV.
Categories: Topoisomerase II InhibitorsPhenelzine
go.drugbank.com/drugs/DB00780ApprovedInvestigationalPhenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder. … [A15753] It was developed by Parke Davis and originally FDA approved on June 9th, 1961. It is currently approved under prescription by the name of Nardil.
Categories: Monoamine Oxidase A SubstratesPhosphatidyl serine
go.drugbank.com/drugs/DB00144ApprovedNutraceuticalPS has been investigated in a small number of double-blind placebo trials and has been shown to increase memory performance in the elderly. … Phosphatidyl serine (PS) is a phospholipid nutrient found in fish, green leafy vegetables, soybeans and rice, and is essential for the normal functioning of neuronal cell membranes and activates Protein
Terazosin
go.drugbank.com/drugs/DB01162ApprovedInvestigationalTerazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate[A176837]. … Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label][A176831].
Categories: Drugs Used in Benign Prostatic HypertrophyProducts: TERAZOSIN 1A PHARMA 2MG, TERAZOSIN 1A PHARMA 5MGIdronoxil
go.drugbank.com/drugs/DB04915InvestigationalIdronoxil is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called signal transduction inhibitors.
Spirapril
go.drugbank.com/drugs/DB01348ApprovedInvestigationalACE inhibitors are used primarily in treatment of hypertension and congestive heart failure. … Spirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration.
Categories: Agents Acting on the Renin-Angiotensin SystemMedium-chain triglycerides
go.drugbank.com/drugs/DB13959ApprovedInvestigational[A246688] MCTs are used in parenteral nutrition therapy: they serve as a source of calories and essential fatty acids in conditions associated with malnutrition and malabsorption.[L41340] … In the body, MCTs are broken down into glycerol and free fatty acids, which are directly absorbed into the blood stream and transported to the target organs to exert a range of biological and metabolic
Mixtures: LIPOPLUS 20% ( EMULSION PARA PERFUSION IV.), LIPOPLUS 20% ( EMULSION PARA PERFUSION IV.)Zoliflodacin
go.drugbank.com/drugs/DB12817ApprovedInvestigational[A275268] Zoliflodacin is a first-in-class spiropyrimidinetrione antibiotic designed to address this need by inhibiting bacterial type II topoisomerases (DNA gyrase and topoisomerase IV), thereby blocking … [A274938,L54748] It is indicated as a single-dose oral therapy for the treatment of uncomplicated urogenital gonorrhea.
Categories: Topoisomerase II InhibitorsSodium/Potassium Transporting ATPase
go.drugbank.com/bio_entities/BE0010055TargetTransporterHumansIn addition, acts as a homotypic cell adhesion molecule in epithelia cells. … Plays a role in innate immunity by enhancing virus-triggered induction of interferons (IFNs) and interferon stimulated genes (ISGs).
Synonyms: Adhesion molecule in gliaBetamethasone phosphate
go.drugbank.com/drugs/DB14669ApprovedVet approvedBetamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible [betamethasone] to agonize glucocorticoid receptors. … [L11994] Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.[L11994]