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Silodosin
go.drugbank.com/drugs/DB06207ApprovedInvestigationalSilodosin is a selective antagonist of alpha(α)-1 adrenergic receptors that binds to the α<sub>1A</sub> subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder … [A231159] Silodosin was first approved by the FDA in October 2008 [A231159] and it is also approved in Europe and Canada.
Categories: Drugs Used in Benign Prostatic Hypertrophy, Cytochrome P-450 SubstratesProducts: SILODOSINA EG, SILOPROST® 8Spirapril
go.drugbank.com/drugs/DB01348ApprovedInvestigationalACE inhibitors are used primarily in treatment of hypertension and congestive heart failure. … Spirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration.
Categories: Agents Acting on the Renin-Angiotensin SystemElvitegravir
go.drugbank.com/drugs/DB09101ApprovedInvestigationalElvitegravir is a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI) used for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. … Although available as a single dose tablet, elvitegravir must be used in combination with an HIV protease inhibitor coadministered with ritonavir and another antiretroviral drug.
Synonyms: 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acidMixtures: GENVOYA ® TABLETAS RECUBIERTAS, STRIBILD® TABLETAS RECUBIERTASZiconotide
go.drugbank.com/drugs/DB06283ApprovedInvestigational[A202835, L13389] Other such peptides, collectively termed conotoxins, exist, and some have shown efficacy in binding specific subsets of calcium channels; ziconotide is used in part because it can be … [A202829, A202832] Ziconotide is used to manage severe chronic pain refractory to other methods, through its ability to inhibit N-type calcium channels involved in nociceptive signalling.
Categories: Compounds used in a research, industrial, or household setting, Calcium Channels, N-TypeInfluenza B virus B/Massachusetts/2/2012 BX-51B hemagglutinin antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB14397ApprovedInactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. … Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals.
Synonyms: Influenza B virus B/Massachusetts/2/2012 BX-51B hemagglutinin antigen (formaldehyde inactivated)Mixtures: FluVaccinol Subunit Tetra Injektionssuspension in einer FertigspritzeHistamine
go.drugbank.com/drugs/DB05381ApprovedInvestigationalIt is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. … A depressor amine derived by enzymatic decarboxylation of histidine.
Synonyms: 2-(4-imidazolyl)ethylamine, 4-imidazoleethylamineMixtures: MIKES Ponos Pain Relief Cream Roll-On, Histamine DHCl 0.10 Percent and Menthol 2 PercentMLN8054
go.drugbank.com/drugs/DB13061InvestigationalMLN8054 has been used in trials studying the treatment of Colon Neoplasm, Breast Neoplasm, Bladder Neoplasm, Pancreatic Neoplasm, and Advanced Malignancies.
Categories: Heterocyclic Compounds, 2-RingMagnesium citrate
go.drugbank.com/drugs/DB11110ApprovedInvestigational[L2831] It is also considered as an active ingredient in over-the-counter products.[L1113] … Magnesium citrate is a low volume and osmotic cathartic agent.
Mixtures: Min-tran Tab, Q-10 PlusProducts: BET-R-PREP Magnesium Citrate OralTolevamer
go.drugbank.com/drugs/DB01344ApprovedIt may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. … Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels.
Categories: Compounds used in a research, industrial, or household setting, Ion Exchange ResinsSynonyms: poly(styrene-4-sulfonic acid)Influenza A virus A/Texas/50/2012 X-223A (H3N2) hemagglutinin antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB14389ApprovedInactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. … Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals.
Mixtures: FluVaccinol Subunit Tetra Injektionssuspension in einer FertigspritzeSynonyms: Influenza A virus A/Texas/50/2012 X-223A (H3N2) hemagglutinin antigen (formaldehyde inactivated)