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Fluticasone furoate
go.drugbank.com/drugs/DB08906ApprovedInvestigationalFluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label][F4364]. Fluticasone furoate was first approved in 2007[L5965].
Categories: Corticosteroids for inhalation use, Drugs for Obstructive Airway DiseasesDexchlorpheniramine
go.drugbank.com/drugs/DB13679InvestigationalThe salt form dexchlorpheniramine maleate as the active ingredient is available as a prescription drug indicated for adjunctive therapy for allergic and anaphylactic reactions. … It disrupts histamine signaling by competing with histamine for cell receptor sites on effector cells.
Categories: Antihistamines for Systemic UseHydromorphone
go.drugbank.com/drugs/DB00327ApprovedIllicitInvestigational[A176495] The first reported approved product containing hydromorphone in the form of hydromorphone hydrochloride was developed by Fresenius Kabi USA and FDA approved in 1984.[L5795]
Categories: Heterocyclic Compounds with 4 or More RingsUbidecarenone
go.drugbank.com/drugs/DB09270ApprovedInvestigationalNutraceuticalIt is fundamental for cells that have a high metabolic demand. … [A31413] The ubidecarenone is the coenzyme destined for mitochondrial enzyme complexes involved in oxidative phosphorylation in the production of ATP.
Mixtures: Folic-KLancovutide
go.drugbank.com/drugs/DB05029InvestigationalLancovutide, a peptide antibiotic, is in clinical development for the treatment of cystic fibrosis.
Enalaprilat
go.drugbank.com/drugs/DB09477ApprovedInvestigationalEnalaprilat is poorly orally available and is therefore only available as an intravenous injection for the treatment of hypertension when oral therapy is not possible. … As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of the kidney, down-regulation of this protein results in reduced blood pressure and blood fluid volume
Categories: Antihypertensive Agents Indicated for HypertensionZuclopenthixol
go.drugbank.com/drugs/DB01624ApprovedInvestigationalZuclopenthixol was approved for use in Canada in 2011, but is not approved for use in the United States. … Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent.
Dimethicone 410
go.drugbank.com/drugs/DB14005Approved[L2162] The name dimethicone has a lot of nomenclature inconsistencies as it is used to refer to common names, generic names, trade names or even for the listing of mixtures. … [L1769] It is currently recognized by the FDA as a skin protectant OTC ingredient for human use in a concentration of 1-30%.
Pitavastatin
go.drugbank.com/drugs/DB08860ApprovedInvestigationalas well as the need for surgical revascularization or angioplasty following a heart attack. … events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks.
Categories: Hypolipidemic Agents Indicated for HyperlipidemiaDaridorexant
go.drugbank.com/drugs/DB15031ApprovedInvestigationalConventional treatments for insomnia include drugs targeting gamma-aminobutyric acid type-A (GABA-A), serotonin, histamine, or melatonin receptors; however, undesirable side effects are frequently reported … Insomnia is characterized by difficulties with sleep onset and/or sleep maintenance and impairment of daytime functioning.