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Trimebutine
go.drugbank.com/drugs/DB09089ApprovedInvestigationalTrimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. … Trimebutine is not a FDA-approved drug, but it is available in Canada and several other international countries.
Synonyms: 2-Dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoatSalts: Trimebutine 3-thiocarbamoylbenzenesulfonateBilastine
go.drugbank.com/drugs/DB11591ApprovedBilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.
Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingProducts: ELHIST ® 20 MG, NAIRE® 20 MG TABLETALevetiracetam
go.drugbank.com/drugs/DB01202ApprovedInvestigationalmake it a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in drug interactions. … It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingProducts: 6-UR, CEUMID® CONCENTRADO PARA SOLUCIÓN PARA PERFUSIÓN 500 MG / 5 MLDesmopressin
go.drugbank.com/drugs/DB00035ApprovedInvestigationalOn January 15, 2026, the FDA approved a new low-dose sublingual film formulation specifically for the treatment of nocturia in patients at high risk for fluid overload, utilizing a specialized delivery … Desmopressin is primarily indicated for the treatment of central diabetes insipidus, primary nocturnal enuresis (bedwetting) in children, and nocturia in adults [A275458, L56104].
Synonyms: 1 deamino 8 D argininevasopressin, 1-(3-mercaptopropionic acid)-8-D-arginine-vasopressinProducts: NOCDURNA 25 MCG ORAL LYOPHILISATE, Nocdurna 25 Mikrogramm – Lyophilisat zum EinnehmenDoxylamine
go.drugbank.com/drugs/DB00366ApprovedInvestigationalVet approvedIt is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Synonyms: N,N-Dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine, Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl etherMixtures: Cold and Flu Nighttime Severe, 24-7 Life, Robitussin Maximum Strength Severe Multi-Symptom 7 in 1 Relief NighttimeMethenamine
go.drugbank.com/drugs/DB06799ApprovedInvestigationalVet approvedMethenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. … In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Mixtures: PURINOL 250 mg+615 mg/5 g EFERVESAN 70 GR, PURINOL 250 mg+615 mg/5 g EFERVESAN 70 GRProducts: NETURONE GRANUL LIBA, 70 G, URON 500 MG TABLET, 21 ADETGriseofulvin
go.drugbank.com/drugs/DB00400ApprovedVet approvedAn antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
International brands: Grison-250, S-FulvinCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP1A2 InducersEthosuximide
go.drugbank.com/drugs/DB00593ApprovedInvestigationalAn anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 2-ethyl-2-methylsuccinimide, (±)-2-ethyl-2-methylsuccinimideFluphenazine
go.drugbank.com/drugs/DB00623ApprovedA phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Synonyms: 10-(3-(2-hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine, 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanolInternational brands: Dapotum DTamsulosin
go.drugbank.com/drugs/DB00706ApprovedInvestigational[A178351] Tamsulosin was first approved by the FDA on April 15, 1997.[L6238] … [Label] Other alpha-1 adrenoceptor antagonists developed in the 1980s were less selective and more likely to act on the smooth muscle of blood vessels, resulting in hypotension.
Synonyms: (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide, (R)-(−)-tamsulosinInternational brands: Harnal D