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Semaglutide
go.drugbank.com/drugs/DB13928ApprovedInvestigational[L8678] The subcutaneous injection is administered once weekly and the tablet is administered once a day. … Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity.
Categories: Glucagon-like peptide-1 (GLP-1) analogues, GLP-1 AgonistsProducts: RYBELSUS® 3 MG TABLETAS, RYBELSUS® 7 MG TABLETASDicloxacillin
go.drugbank.com/drugs/DB00485ApprovedInvestigationalVet approvedOne of the penicillins which is resistant to penicillinase.
Categories: Cytochrome P-450 CYP3A Inducers, Heterocyclic Compounds, 2-RingSynonyms: (2S,5R,6R)-6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidColestipol
go.drugbank.com/drugs/DB00375Approved, colestipol is still generally only employed as an adjunct therapy and the relatively physical nature of its pharmacological activity sometimes limits its usefulness. … [FDA Label, F4555, F4567, L6262] In particular, as colestipol's general mechanism of action ultimately results in the decreased absorption and enhanced secretion of bile acids and lipids in the feces
Categories: Compounds used in a research, industrial, or household settingSynonyms: Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxiraneRasagiline
go.drugbank.com/drugs/DB01367ApprovedInvestigationalRasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesSynonyms: (R)-N-2-Propynyl-1-indanamine, (R)-indan-1-yl-prop-2-ynyl-amineVusolimogene oderparepvec
go.drugbank.com/drugs/DB23008ApprovedInvestigational[L64061,L64062] It is the second oncolytic viral therapy approved in the United States, following talimogene laherparepvec (T-VEC, Imlygic) in 2015, and the first approved for melanoma that has progressed … [L64061] The virus is engineered to express a fusogenic glycoprotein derived from gibbon ape leukemia virus (GALV-GP-R–) and human granulocyte-macrophage colony-stimulating factor (GM-CSF), and has its
Synonyms: Hsv-1 oncolytic viral strain rp1Oxtriphylline
go.drugbank.com/drugs/DB01303ApprovedIt is marketed under the name Choledyl SA, and several forms of oxytriphylline have been discontinued. In the US, oxtriphylline is no longer available. … Its main physiological reponse is to dilate the bronchioles. As such, oxytriphylline is indicated mainly for asthma, bronchospasm, and COPD (i.e. all the same indications as the other theophyllines).
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingSynonyms: Teofilinato de colina, Theophyllinate de cholineTilactase
go.drugbank.com/drugs/DB13761ApprovedInvestigationalTilactase is a beta-D-galactosidase obtained from _Aspergillus oryzae_. It is produced as a chewable tablet that has to be taken before the consumption of a lactose-containing meal. … [A32591] It is considered by the WHO as part of the International Nonpropietary Names for Pharmaceutical Substances.[L2338]
Synonyms: beta-D-GalactosidaseProducts: LACDIGEST 2250 U CIGNEME TABLETI, 100 TABLET, LACDIGEST 2250 U CIGNEME TABLETI, 50 TABLETMedrogestone
go.drugbank.com/drugs/DB09124ApprovedWithdrawn[L1118] It was never approved by the FDA. … Medrogestone (INN), also known as 6,17α-dimethyl-6-dehydroprogesterone, is a progestational agent derived from 17-methylprogesterone.
Categories: Sex Hormones and Modulators of the Genital System, Cytochrome P-450 SubstratesElafibranor
go.drugbank.com/drugs/DB05187ApprovedInvestigationalElafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist [A263833] that works to inhibit bile acid synthesis. … [L50773] The drug was also approved by the EMA on September 23, 2024.[L51878]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: PROPANOIC ACID, 2-(2,6-DIMETHYL-4-((1E)-3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)-, PROPANOIC ACID, 2-(2,6-DIMETHYL-4-(3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)-2-METHYL-Momelotinib
go.drugbank.com/drugs/DB11763ApprovedInvestigational[A261566] First approved by the FDA on September 15, 2023,[L48206] momelotinib is used to treat myelofibrosis. … [L48186] Myelofibrosis (MF) is a group of myeloproliferative neoplasms characterized by abnormal proliferative hematopoietic stem cells, leading to the release of cytokines and growth factors.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: N-(CYANOMETHYL)-4-(2-(4-MORPHOLINOANILINO)PYRIMIDIN-4-YL)BENZAMIDE