Dicloxacillin is a penicillin used to treat penicillinase-producing bacterial infections that are susceptible to the drug. One of the penicillins which is resistant to penicillinase.
- Mechanism
- Curator reviewed
Dicloxacillin exerts a bactericidal action against penicillin-susceptible microorganisms during the state of active multiplication. All penicillins inhibit the biosynthesis of the bacterial cell wall. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, dicloxacillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that dicloxacillin interferes with an autolysin inhibitor.
- Primary indication
- Used to treat infections caused by penicillinase-producing staphylococci which have demonstrated susceptibility to the drug.Curator reviewed · 1 structured indication
- Formula / weight
- C19H17Cl2N3O5S · 470.326 g/mol (avg)
- First approval
- United States, 1971
- Code names
- Bayer 5488 · BRL-1702 · P 1011 · R-13423
Resolves to
YFAGHNZHGGCZAX-JKIFEVAISA-NSMILES[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C1=C(C)ON=C1C1=C(Cl)C=CC=C1Cl)C(O)=OWhat you can answer from here — as of September 23, 2026
Which drugs share a target with Dicloxacillin, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account