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GET-73
go.drugbank.com/drugs/DB12928InvestigationalGet 73 has been investigated for the treatment of Alcohol Dependence.
FT-1101
go.drugbank.com/drugs/DB17553InvestigationalFT-1101 is a novel Bromodomain and Extra-Terminal motif (BET) inhibitor. … [A257301] FT-1101 is under investigation in clinical trial NCT02543879 (Study of a Novel BET Inhibitor FT-1101 in Patients With Relapsed or Refractory Hematologic Malignancies).
Mebanazine
go.drugbank.com/drugs/DB09248ApprovedWithdrawnIt was used in the past as an antidepressant in the 1960s, but has since been discontinued because of its hepatotoxic potential. … Mebanazine, also known as _Actomol_, is a monoamine oxidase inhibitor (MAOI) belonging to the _hydrazine_ class of chemicals.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeWarfarin
go.drugbank.com/drugs/DB00682ApprovedInvestigationalWarfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. … Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: VARFARİN 5 MG TABLET, 20 ADET, VARFARİN 5 MG TABLET, 50 ADETZuranolone
go.drugbank.com/drugs/DB15490ApprovedInvestigational[A260776,A260786] Zuranolone was designed with a pharmacological profile of a neuroactive steroid in mind while also possessing a pharmacokinetics profile of an oral, once-daily dosing formulation. … Unlike other more common GABA<sub>A</sub> positive allosteric modulators on the market like benzodiazepines, zuranolone can modulate both synaptic and extrasynaptic GABA<sub>A</sub> conductance due to
Categories: Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive ModulatorThymidine
go.drugbank.com/drugs/DB04485ApprovedInvestigationalThymidine is a naturally occurring deoxyribonucleoside that is a crucial component of the DNA salvage pathway and a building block for DNA synthesis. … [A274683, A274688] As of now, its primary role is in research and as a sensitizer or modulator in experimental chemotherapy regimens, rather than a standalone, approved therapeutic agent.
Picosulfuric acid
go.drugbank.com/drugs/DB09268ApprovedInvestigationalSodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels before colonoscopy or surgery.
Mixtures: AGAROL CON SABOR A FRAMBUESA, CITRAFLEET 0.01 G/ 3.50 G/ 10.97 G ORAL ÇÖZELTI HAZIRLAMAK IÇIN TOZ IÇEREN SAŞE , 2 ADETProducts: Laxapico 2,5 mg Yumuşak Kapsül, 50 adet, DULCOLAX 2.5 MG YUMUSAK JELATIN KAPSUL, 50 ADETPivhydrazine
go.drugbank.com/drugs/DB09252ApprovedWithdrawnIn 1960, it was widely used as an antidepressant agent but it is now discontinued. … Pivhydrazine, also known as pivazide, is a member of the hydrazine family with irreversible and non-selective inhibitory activity against monoamine oxidases.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeDeucravacitinib
go.drugbank.com/drugs/DB16650ApprovedInvestigational[A246938, A246943] This selectivity towards TYK2 may lead to an improved safety profile of deucravacitinib, as nonselective JAK inhibitors are associated with a range of adverse effects such as altered … cholesterol and triglyceride levels and liver and kidney dysfunction.
Iobenguane
go.drugbank.com/drugs/DB06704ApprovedInvestigationalThe radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. … Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved on September 19, 2008.
Categories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of Chemicals