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Almonertinib
go.drugbank.com/drugs/DB16640ApprovedInvestigational[A231859] On March 19, 2020, almonertinib was approved in China for the treatment of EGFR T790M+ non-small cell lung cancer.[A231864] Almonertinib was also approved by the EMA on February 20, 2026. … [A231859, A231864, A231869] Unlike other third-generation EGFR TKIs, almonertinib is a pyrimidine-based drug that forms a covalent bond to the binding site of the EGFR tyrosine kinase domain.
Categories: MATE 1 Inhibitors, P-glycoprotein inhibitorsSynonyms: 2-Propenamide, N-[5-[[4-(1-cyclopropyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-, N-[5-[[4-(1-Cyclopropyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-2-propenamideEconazole
go.drugbank.com/drugs/DB01127ApprovedA broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally.
Mixtures: Econazole Nitrate 1% / Niacinamide 4%, 071023 Econazole Nitrate 1% / Niacinamide 4%Categories: combinations of imidazole derivatives, Metabolic Side Effects of Drugs and SubstancesHomosalate
go.drugbank.com/drugs/DB11064ApprovedHomosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage and increased risk of skin cancer. It is a common ingredient in many commercially available sunscreens. … Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol.
Mixtures: Sea Results Line Resolution Sea Results Line Resolution SPF30, REDEFINE Regimen for the Appearance of Lines, Pores and Loss of Firmness Travel SizeCategories: Compounds used in a research, industrial, or household settingEucalyptol
go.drugbank.com/drugs/DB03852ApprovedInvestigationalNutraceuticalEucalyptol is naturally produced cyclic ether and monoterpenoid. Eucalyptol is an ingredient in many brands of mouthwash and cough suppressant. … It kills leukaemia cells in vitro.
Mixtures: Marcs Original, Marcs Blue MintCategories: Compounds used in a research, industrial, or household settingCalcium citrate
go.drugbank.com/drugs/DB11093ApprovedInvestigationalCalcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements.
Mixtures: Calcium-magnesium With K & Zn and Vitamin D3, CALCIBON® MINCategories: Compounds used in a research, industrial, or household setting, ascorbic acid (vit C) and calciumMoexipril
go.drugbank.com/drugs/DB00691ApprovedInvestigationalMoexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). … It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
Mixtures: CO RENOPROTECCategories: Agents Acting on the Renin-Angiotensin System, Heterocyclic Compounds, 2-RingLenalidomide
go.drugbank.com/drugs/DB00480ApprovedInvestigationalzone lymphoma in selected patients. … [A228553] It is a 4-amino-glutamyl analogue of [thalidomide] [A228543] and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms.
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingSynonyms: 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline, 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dioneOctocrylene
go.drugbank.com/drugs/DB09535ApprovedOctocrylene is a compound often used as an additive in sun screen, and is thought to have skin moisturizing effects because of its emollient properties. … Because of its effectiveness, the chemical has been approved across the globe for use in cosmetics and skin care products, but the concentrations of this ingredient are usually limited to no more than
Mixtures: Marc Jacobs Lip Lock Moisture BalmSPF 18 SPF 18, For Men Maca Root Energetic Face Protector SPF 15Products: Panama Jack SPF 4, Panama Jack SPF 4 Dark Tanning OilAIDS-related Kaposi's Sarcoma
go.drugbank.com/conditions/DBCOND0025353Drugs: DoxorubicinSynonyms: HIV disease resulting in Kaposi's sarcoma (disorder)Enoxacin
go.drugbank.com/drugs/DB00467ApprovedA broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Categories: Topoisomerase II Inhibitors, Metabolic Side Effects of Drugs and SubstancesSynonyms: 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid, 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid