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Displaying results 2101 - 2110 of 10000 in total
  1. Pathway

    Cardiolipin Biosynthesis CL(8:0/24:0/i-24:0/i-24:0)

    smpdb.ca/view/SMP0288200
    Metabolic

    Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  2. Pathway

    Cardiolipin Biosynthesis CL(i-15:0/24:0/24:0/i-24:0)

    smpdb.ca/view/SMP0288254
    Metabolic

    Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  3. Drug

    TERN-101

    go.drugbank.com/drugs/DB16045
    Investigational

    TERN-101 is under investigation in clinical trial NCT04328077 (LIFT Study: A Safety, Tolerability, Efficacy, and Pharmacokinetics Study of TERN-101 in Subjects With Non-cirrhotic Non-alcoholic Steatohepatitis

  4. Drug

    TZ-101

    go.drugbank.com/drugs/DB18690
    Experimental

    TZ-101 composes of [GDP-L-fucose] and fucosyltransferase VI

  5. Drug

    ST-101

    go.drugbank.com/drugs/DB12621
    Investigational

    ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease.[A260411]

    Synonyms: ST-101 (D-AMINO ACID PEPTIDE)
  6. Pathway

    Phosphatidylethanolamine Biosynthesis PE(24:0/24:0)

    smpdb.ca/view/SMP0015865
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phospha...

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  7. Drug

    Blinatumomab

    go.drugbank.com/drugs/DB09052
    ApprovedInvestigational

    [A254836,L44311] CD3 is an antigen expressed on the surface of T-cells, while CD19 is mostly expressed on the surface of malignant B-cells. … Since blinatumomab has an affinity to both antigens, it redirects T-cells to tumor cells expressing CD19 and promotes tumor cell lysis and apoptosis.

    Categories: Bispecific CD19-directed CD3-directed T Cell EngagerProducts: BLINCYTO® 38.5 MCG/VIAL, BLINCYTO POWDER FOR INFUSION 35 MCG/VIAL
  8. Drug

    AMP-101

    go.drugbank.com/drugs/DB18253
    Experimental

    AMP-101 is a gene therapy comprising an adeno-associated virus type 9 (AAV9) vector encoding the human Dok-7 protein. It is under investigation for the treatment of Dok-7-associated myasthenia.

  9. Drug

    RAP-103

    go.drugbank.com/drugs/DB28444
    Experimental

    RAP-103 is a multi-chemokine receptor antagonist which is orally active.[A274606, A274611]

  10. Pathway

    De Novo Triacylglycerol Biosynthesis TG(24:1(15Z)/24:1(15Z)/24:1(15Z))

    smpdb.ca/view/SMP0023959
    Metabolic

    A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate