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Displaying results 2111 - 2120 of 10000 in total

Drug
Diacerein
go.drugbank.com/drugs/DB11994
ApprovedInvestigationalWithdrawn
Diacerein is a prodrug which is metabolized to rhein. … It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including severe diarrhea [L780].
Mixtures: CARTIGEN NFProducts: ARTRODAR 50 MG KAPSUL, 30 ADET
Drug
Iobenguane
go.drugbank.com/drugs/DB06704
ApprovedInvestigational
The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. … Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved on September 19, 2008.
Categories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of Chemicals
Drug
Aminophenazone
go.drugbank.com/drugs/DB01424
ApprovedWithdrawn
Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. … The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening side effect.[A254242,L43942]
Drug
Canertinib
go.drugbank.com/drugs/DB05424
Investigational
Canertinib treatment significantly affects tumour metabolism, proliferation and hypoxia as determined by PET. … Canertinib is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo.
Categories: Compounds used in a research, industrial, or household setting
Drug
Deucravacitinib
go.drugbank.com/drugs/DB16650
ApprovedInvestigational
[A246938, A246943] This selectivity towards TYK2 may lead to an improved safety profile of deucravacitinib, as nonselective JAK inhibitors are associated with a range of adverse effects such as altered … cholesterol and triglyceride levels and liver and kidney dysfunction.
Drug
Prednisolone phosphate
go.drugbank.com/drugs/DB14631
ApprovedInvestigationalVet approved
Prednisolone phosphate is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.
Mixtures: OFTALETYC® NFProducts: MINIMS PREDNISOLONE SODIUM PHOSPHATE EYE DROPS 0.5% w/v
Drug
Lenograstim
go.drugbank.com/drugs/DB13144
ApprovedWithdrawn
Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Products: GRANOCYTE 34 MU ENJEKSİYONLUK/İNFÜZYONLUK LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET
Drug
Trypsin
go.drugbank.com/drugs/DB11237
ApprovedInvestigationalVet approved
Trypsin is a serine protease that plays an essential role in protein hydrolysis and absorption in mammals. … When converted from its zymogen trypsinogen, trypsin is available as an active peptide hydrolase (EC 3.4.21.4) form to cleave peptide chains, mainly at the carboxyl side of the amino acids lysine or arginine
Categories: Preparations for Treatment of Wounds and Ulcers
Drug
Janssen COVID-19 Vaccine
go.drugbank.com/drugs/DB15857
ApprovedInvestigational
The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. … The Janssen COVID-19 vaccine is available under an Emergency Use Authorization (EUA) in the US.[L41745]
Drug
Fomivirsen
go.drugbank.com/drugs/DB06759
ApprovedWithdrawn
As a complementary nucleotide to the messenger RNA of the major immediate-early region proteins of human cytomegalovirus, it disrupts the replication of the virus through an antisense mechanism [L1428] … It is an antiviral agent that was used in the treatment of cytomegalovirus retinitis (CMV) in immunocompromised patients, including those with AIDS.
Categories: Compounds used in a research, industrial, or household setting