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Displaying results 2141 - 2150 of 10000 in total
  1. Drug

    Phentolamine

    go.drugbank.com/drugs/DB00692
    ApprovedInvestigational

    Phentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. … While initially introduced to the market for the treatment of hypertension, this clinical use was halted due to cardiovascular and gastrointestinal adverse effects with the prolonged use of large oral

    Categories: Peripheral alpha-1 blockers, Heterocyclic Compounds, 1-RingSynonyms: 2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazoline, 3-((4,5-DIHYDRO-1H-IMIDAZOL-2-YLMETHYL)(4-METHYLPHENYL)AMINO)PHENOL
  2. Drug

    Nelonicline

    go.drugbank.com/drugs/DB19040
    Investigational

    Nelonicline is under investigation in clinical trial NCT01678755 (A Phase 2 Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia).

    Synonyms: 2-((3r,4s,5s,7s)-1-azaadamantan-4-yloxy)-5-phenyl-1,3,4-thiadiazole, rel-Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    SR-9011

    go.drugbank.com/drugs/DB14014
    Experimental

    SR-9011 is a REV-ERB agonist.

    Synonyms: 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    R-348

    go.drugbank.com/drugs/DB06321
    Investigational

    Synonyms: 5-Fluoro-N-(4-methyl-3-propionylaminosulfonylphenyl)-N'-(4-(prop-2-ynyloxy)phenyl)-2,4-pyrimidinediamine
  5. Drug

    Rocbrutinib

    go.drugbank.com/drugs/DB19445
    Investigational

    Rocbrutinib is under investigation in clinical trial NCT05716087 (A Study of Rocbrutinib in Participants With Relapse or Refractory Mantle Cell Lymphoma).

    Synonyms: -2H-pyran-4-yl)-1-piperazinyl]phenyl]-2-propena, 2-Propenamide, N-[5-[[6-[2-(1,3,4,6,7,8-hexahydro-7,7-dimethyl-1-oxo-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl)-3-(hydroxymethyl)-4-pyridinyl]-3,4-dihydro-4-methyl-3-oxo-2-pyrazinyl]amino]-2-[(2S)-2
  6. Drug

    Timolol

    go.drugbank.com/drugs/DB00373
    ApprovedInvestigational

    [L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978. … Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes.

    Mixtures: Vizidor Duo 20 mg/ml + 5 mg/ml Augentropfen, Combigan 2 mg/ml + 5 mg/ml AugentropfenCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  7. Drug

    Simvastatin

    go.drugbank.com/drugs/DB00641
    ApprovedInvestigational

    [A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks.

    Mixtures: EXOTIB-DUO, VYTORIN ® 10/20 MGCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  8. Drug

    Glutamic acid

    go.drugbank.com/drugs/DB00142
    ApprovedInvestigationalNutraceutical

    A peptide that is a homopolymer of glutamic acid.

    Mixtures: AMINOPLASMAL-5% E INFUSION, PEPZAN 225 MG/225 MG FİLM TABLET, 20 ADETSynonyms: (S)-2-Aminopentanedioic acid, L-Glutamate
  9. Drug

    5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE

    go.drugbank.com/drugs/DB06958
    Experimental

    Synonyms: 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE
  10. Drug

    Loxapine

    go.drugbank.com/drugs/DB00408
    ApprovedInvestigational

    An antipsychotic agent used in schizophrenia. [PubChem]

    Synonyms: 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepineCategories: Dopamine D2 Receptor Antagonists, Serotonin 5-HT2 Receptor Antagonists