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Segesterone acetate
go.drugbank.com/drugs/DB14583ApprovedAnnovera™ is administered as a vaginal ring that is in place for 21 days and removed for 7 days each cycle. … According to the Center for Disease Control, more than 43 million women in the U.S. are at risk of unintended pregnancy, which may be associated with an elevated risk for improper prenatal care, premature
Categories: Hormonal Contraceptives for Systemic UseCocaine
go.drugbank.com/drugs/DB00907ApprovedIllicitInvestigationalIt is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat.
Voxelotor
go.drugbank.com/drugs/DB14975ApprovedVoxelotor is a novel hemoglobin S polymerization inhibitor for the treatment of sickle cell disease. … The EMA approved the use of voxelotor for the treatment of hemolytic anemia associated with sickle cell disease in February 2022.[L41419,L41424]
Nomegestrol acetate
go.drugbank.com/drugs/DB13981ApprovedNomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Categories: Hormonal Contraceptives for Systemic UseClobazam
go.drugbank.com/drugs/DB00349ApprovedIllicitInvestigational[A256958] In 2005, clobazam also received approval from Health Canada as an add-on therapy for generalized tonic-clonic, myoclonic, and focal impaired awareness seizures.[A256978] … [A521,A522] In October 21, 2011, the FDA approved clobazam as an adjunctive treatment for seizures associated with Lennox-Gastaut syndrome in adults and children aged two years and older.
Categories: GABA-A Receptor AgonistsLymecycline
go.drugbank.com/drugs/DB00256ApprovedInvestigationalWithdrawnLymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseZucapsaicin
go.drugbank.com/drugs/DB09120ApprovedWithdrawnZucapsaicin has also been evaluated for the management of several conditions manifested by chronic nerve pain. … It is a modulator of transient receptor potential cation channel subfamily V member 1 (TRPV-1), also known as the vanilloid or capsaicin receptor 1, that reduces pain and improves articular functions.
Categories: Topical Products for Joint and Muscular PainVoretigene neparvovec
go.drugbank.com/drugs/DB13932ApprovedInvestigationalThis type of virus is vastly used as vectors for gene therapy because they can infect dividing and quiescent cell integrating just the carried genes into the host genome without fully integrating into … When used in genetic therapy, this virus is modified for the elimination of its negligible integrative capacity by the removal of *rep* and *cap* and the insertion of the desired gene with its promoter
Nomifensine
go.drugbank.com/drugs/DB04821ApprovedWithdrawnFDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal Register of June 17, 1986 (51 FR 21981)). … Approval of the NDA for Merital capsules was withdrawn on March 20, 1992 (see the Federal Register of March 20, 1992 (57 FR 9729)). Also withdrawn from the Canadian and UK markets.
Gentian violet cation
go.drugbank.com/drugs/DB00406ApprovedA dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
Categories: Antifungals for Topical Use, Antifungals for Dermatological Use