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RWJ-56423
go.drugbank.com/drugs/DB02812ExperimentalSynonyms: (2S,4R)-1-acetyl-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-hydroxypyrrolidine-2-carboxamideENMD-981693
go.drugbank.com/drugs/DB16891InvestigationalSynonyms: (E)-N-(5-Methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimidin-4-amineCategories: Heterocyclic Compounds, 1-RingElimusertib
go.drugbank.com/drugs/DB19041InvestigationalElimusertib is under investigation in clinical trial NCT05071209 (Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors).
Synonyms: 1,7-naphthyridine, 2-((3r)-3-methyl-4-morpholinyl)-4-(1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-3-yl)-Categories: Heterocyclic Compounds, 1-RingFosmanogepix
go.drugbank.com/drugs/DB15183InvestigationalFosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia).
Synonyms: [2-amino-3-[3-[[4-(2-pyridyloxymethyl)phenyl]methyl]isoxazol-5-yl]pyridin-1-ium-1-yl]methyl hydrogen phosphateTomivosertib
go.drugbank.com/drugs/DB15219InvestigationalTomivosertib is under investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC).
Categories: Heterocyclic Compounds, 1-RingSynonyms: 6'-((6-Amino-4-pyrimidinyl)amino)-8'-methyl-2'H-spiro(cyclohexane-1,3'-imidazo(1,5-a)pyridine)-1',5'-dioneAnlotinib
go.drugbank.com/drugs/DB11885InvestigationalAnlotinib has been investigated for the treatment of Non-small Cell Lung Cancer and Metastatic Colorectal Cancer.
Synonyms: 1-((4-(4-fluoro-2-methyl-1h-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropan-amineCategories: Heterocyclic Compounds, 2-RingFimepinostat
go.drugbank.com/drugs/DB11891InvestigationalFimepinostat (CUDC-907) has been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and NUT midline carcinoma, among others.
Synonyms: 5-pyrimidinecarboxamide, N-hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]methylamino]-, N-hydroxy-2-(((2-(6-methoxypyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)(methyl)amino)pyrimidine-5-carboxamideCategories: Phosphatidylinositol 3-Kinases, antagonists & inhibitors, Heterocyclic Compounds, 1-RingOsugacestat
go.drugbank.com/drugs/DB12006InvestigationalOsugacestat (BMS-906024) has been used in trials studying the treatment of Cancer, Lymphoblastic Leukemia, Acute T-cell, and Precursor T-Cell Lymphoblastic Lymphoma.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (2R,3S)-N1-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-2,3-bis(3,3,3-trifluoropropyl)succinamide, Butanediamide, N1-((3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-2,3-bis(3,3,3-trifluorophenyl)-, (2R,3S)-Methylene blue
go.drugbank.com/drugs/DB09241ApprovedInvestigationalMethylene blue is an oxidation-reduction agent. The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. Historically, it has been widely used in Afr...
Synonyms: Basic Blue 9, C.I. basic blue 9Mixtures: BUCO-BLEU KOLLUTUVAR, 15 ML, Me NaPhos MB Hyo 1[2-(1-Amino-2-Hydroxy-Propyl)-4-(4-Fluoro-1h-Indol-3-Ylmethyl)-5-Hydroxy-Imidazol-1-Yl]-Acetic Acid
go.drugbank.com/drugs/DB01674ExperimentalSynonyms: [2-(1-Amino-2-Hydroxy-Propyl)-4-(4-Fluoro-1h-Indol-3-Ylmethyl)-5-Hydroxy-Imidazol-1-Yl]-Acetic Acid