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Displaying results 2181 - 2190 of 10000 in total
  1. Drug

    Estramustine phosphate

    go.drugbank.com/drugs/DB14674
    Approved

    A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.

  2. Drug

    Temsavir

    go.drugbank.com/drugs/DB14675
    Investigational

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  3. Drug

    Cortisone

    go.drugbank.com/drugs/DB14681
    Investigational

    A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. … It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersSynonyms: Kendall's compound E, Wintersteiner's compound F
  4. Drug

    Calcium polycarbophil

    go.drugbank.com/drugs/DB14684
    Approved

    Calcium polycarbophil is a stool stabilizer. … Based on its chemical structure, it is a synthetic polymer of polyacrylic acid cross-linked with divinyl glycol presenting a calcium atom as a counter-ion.

    Categories: Compounds used in a research, industrial, or household settingProducts: FIBROSYL®
  5. Drug

    Ceramide NG

    go.drugbank.com/drugs/DB14706
    Investigational

    Synonyms: Ceramide 2, Ceramide NSMixtures: 5% Oat Facial Cleanser
  6. Drug

    Inotersen

    go.drugbank.com/drugs/DB14713
    ApprovedInvestigational

    Inotersen is a transthyretin-directed antisense oligonucleotide for the treatment of the polyneuropathy caused by hereditary transthyretin-mediated amyloidosis in adults. … Hereditary transthyretin amyloidosis is caused by single-nucleotide variants in the gene encoding transthyretin (TTR), which lead to transthyretin misfolding and the deposition of amyloid substance systemically

  7. Drug

    ADU-S100

    go.drugbank.com/drugs/DB14722
    Investigational

    ADU-S100 (MIW815) is a synthetic cyclic dinucleotide (CDN) agonist (activator) of Stimulator of Interferon Genes (STING), a receptor crucial to activate the innate (endogenous) immune system. … ADU-S100 (MIW815) activates all known human and mouse STINGs, and effectively induces the expression of cytokines and chemokines, leading to a robust and durable antigen-specific T-cell mediated immune

  8. Drug

    Emapalumab

    go.drugbank.com/drugs/DB14724
    ApprovedInvestigational

    Emapalumab, also known as NI-0501, is a fully human monoclonal antibody that targets interferon gamma. … Emapalumab development was sponsored by NovImmune SA, further developed by Sobi and FDA approved on November 20, 2018.

  9. Drug

    Queuine

    go.drugbank.com/drugs/DB14732
    ExperimentalNutraceutical

    Queuine is a derivative of [7-Deazaguanine]. Bacteria possess the exclusive ability to synthesize queuine, which is then salvaged and passed on to plants and animals.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 7-(3,4-trans-4,5-cis-dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-deazaguanine, Base Q
  10. Drug

    Cannabivarin

    go.drugbank.com/drugs/DB14736
    Experimental

    A natural product found in Cannabis sativa.