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Displaying results 211 - 220 of 10000 in total
  1. Drug

    2(S)-Amino-6-Boronohexanoic Acid

    go.drugbank.com/drugs/DB01983
    Experimental

    Synonyms: 2(S)-Amino-6-Boronohexanoic Acid
  2. Drug

    Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine

    go.drugbank.com/drugs/DB16757
    Approved

    [L40694] It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and is mixed with the AS03 adjuvant system prior to administration. … [L40694] While the concept of plant-based VLPs as vaccines is not new,[A245824] it is a novel approach to COVID-19 vaccination, with previously approved COVID-19 vaccines mostly comprising viral vector

    Synonyms: Recombinant SARS-CoV-2 spike (S)-protein virus-like particle
  3. Drug

    Dexrazoxane

    go.drugbank.com/drugs/DB00380
    ApprovedInvestigationalWithdrawn

    [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. … Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex.

    Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingSynonyms: (+)-(S)-4,4'-Propylenedi-2,6-piperazinedione, 2,6-Piperazinedione, 4, 4'-(1-methyl-1,2-ethanediyl)bis-, (S)- (9CI)
  4. Drug

    (E)-(S)-4-[(S)-4-METHYL-2-((S)-3-METHYL-2{(S)-2-[(5-METHYL-ISOXAZOLE-3- CARBONYL)-AMINO]-PROPIONYLAMINO}-BUTYRYLAMINO)-PENTANOYLAMINO]-5-((S)-2- OXO-PYRROLIDIN-3-YL)-PENT-2-ENOIC ACID ETHYL ESTER

    go.drugbank.com/drugs/DB04710
    Experimental

    Synonyms: (E)-(S)-4-[(S)-4-METHYL-2-((S)-3-METHYL-2{(S)-2-[(5-METHYL-ISOXAZOLE-3- CARBONYL)-AMINO]-PROPIONYLAMINO}-BUTYRYLAMINO)-PENTANOYLAMINO]-5-((S)-2- OXO-PYRROLIDIN-3-YL)-PENT-2-ENOIC ACID ETHYL ESTER
  5. Drug

    Azacitidine

    go.drugbank.com/drugs/DB00928
    ApprovedInvestigational

    One of them is the induction of cytotoxicity. As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and inhibiting protein and DNA synthesis. … The other one is through the inhibition of DNA methyltransferase, impairing DNA methylation.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one, 5 Azacitidine
  6. Drug

    Timolol

    go.drugbank.com/drugs/DB00373
    ApprovedInvestigational

    [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management of conditions such as open-angle glaucoma and hypertension. … [L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978.

    Mixtures: COSOPT S 20/5MG/ML, COSOPT S 20MG/ML+5MG/MLCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  7. Drug

    (S)-2-(MERCAPTOMETHYL)-5-PHENYLPENTANOIC ACID

    go.drugbank.com/drugs/DB08161
    Experimental

    Synonyms: (S)-2-(MERCAPTOMETHYL)-5-PHENYLPENTANOIC ACID
  8. Drug

    Carboprost tromethamine

    go.drugbank.com/drugs/DB00429
    ApprovedInvestigational

    A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.

    Categories: Prostaglandins F, SyntheticSynonyms: 15(S)-15-methyl-PGF2α tromethamine salt, 15(S)-15-methylprostaglandin F2α tromethamine
  9. Drug

    Equol

    go.drugbank.com/drugs/DB11674
    Investigational

    Equol has been used in trials studying the treatment of Breast Cancer.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: S-equol
  10. Drug

    Esflurbiprofen

    go.drugbank.com/drugs/DB16159
    Investigational

    Esflurbiprofen is under investigation in clinical trial NCT03434197 (Safety and Efficacy of SFPP in Knee Osteoarthritis).

    Synonyms: Flurbiprofen, (s)-