Esflurbiprofen

DB16159InvestigationalSmall molecule

Esflurbiprofen is an NSAID formulated as a topical product for osteoarthritis associated joint pain and inflammation. Esflurbiprofen is under investigation in clinical trial NCT03434197 (Safety and Efficacy of SFPP in Knee Osteoarthritis).

Chemical structure of Esflurbiprofen
Mechanism
Curator reviewed
Formula / weight
C15H13FO2 · 244.265 g/mol (avg)
Also known as
Flurbiprofen, (s)-
Code names
BTS-24332

Resolves to

Compound
UNIIJ5ZZK9P7MXCAS51543-39-6ChEMBLCHEMBL435298ChEBI42446
Clinical / RWD
ATCM02AA29
Structure
InChIKeySYTBZMRGLBWNTM-JTQLQIEISA-NSMILESC[C@H](C(O)=O)C1=CC(F)=C(C=C1)C1=CC=CC=C1
Targets
P23219PTGS1P35354PTGS2P49810PSEN2P49768PSEN1Q92542NCSTNQ9NZ42PSENENQ8WW43APH1BQ96BI3APH1A

What you can answer from here — as of June 15, 2026

9Protein targetsEach mapped to UniProt, with action and pharmacological action
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8Clinical trialsPhase, status and sponsor resolved per trial
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2Structured indicationsCondition, population, route and combination as fields, not prose
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14ContraindicationsEach with its own population and attribute set
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1Marketed productAcross 1 country and 1 labeller
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1ATC codeIncluding every combination product, plus 3 drug categories
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16+ReferencesStructured and connected to the statements they support
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