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Clofarabine
go.drugbank.com/drugs/DB00631ApprovedInvestigationalClofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed. … It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand.
Products: EVOLTRA 1 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION, NUCLOFAR Clofarabine 1mg/mL Concentrate for Solution for InfusionNivolumab
go.drugbank.com/drugs/DB09035ApprovedInvestigational[L12129] This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation _S228P_ for additional stability and reduced variability.
Products: OPDIVO CONCENTRATE FOR SOLUTION FOR INFUSION 10 MG/ML, Opdivo 10mg/ml, Concentrate for solution for infusionDenosumab
go.drugbank.com/drugs/DB06643ApprovedInvestigationalTwo denosumab biosimilars—Wyost® (denosumab-bbdz) [L53063] and Jubbonti® (denosumab-bbdz)[L53058]—were approved by the FDA in March 2024 for all indications of the reference products Xgeva® and Prolia® … for fracture receiving adjuvant aromatase inhibitor therapy for breast cancer in September 2011 and in men with osteoporosis at high risk for fracture in September 2012.
Categories: Drugs for Treatment of Bone DiseasesProducts: XGEVA 120mg Solution for Injection, XGEVA Solution for Injection 120 mg/vialTedizolid
go.drugbank.com/drugs/DB14569ApprovedInvestigationalThis product is currently available as both an oral tablet and as a powder for intravenous injection.[L11232] … [L11232, A199086, A199050] Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate (SIVEXTRO®).
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: SIVEXTRO LYOPHILIZED POWDER FOR SOLUTION FOR INFUSION 200MG PER VIALDistichlis spicata pollen
go.drugbank.com/drugs/DB10494ApprovedDistichlis spicata pollen is the pollen of the Distichlis spicata plant. Distichlis spicata pollen is mainly used in allergenic testing.
Categories: Grass Pollen Allergen ExtractsSynonyms: salt grass pollen extractBromus secalinus pollen
go.drugbank.com/drugs/DB10836ApprovedBromus secalinus pollen is the pollen of the Bromus secalinus plant. Bromus secalinus pollen is mainly used in allergenic testing.
Mixtures: Number Fourteen Grass MixtureCategories: Grass Pollen Allergen ExtractsAntihemophilic factor (recombinant), PEGylated
go.drugbank.com/drugs/DB09329ApprovedInvestigationalPEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation in the plasma [L1529]. … PEGylation is the covalent attachment of a polyethylene glycol polymer, called PEG, to a drug or protein.
Categories: Compounds used in a research, industrial, or household settingProducts: ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION, ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTIONMepolizumab
go.drugbank.com/drugs/DB06612ApprovedInvestigationalMepolizumab was first approved by the FDA on November 4, 2015, as an add-on therapy for severe asthma and marketed under the brand name Nucala by GlaxoSmithKline. … Activated eosinophils further stimulate an inflammatory response and also induce tissue lesions and promote fibrosis, all of which contribute to the multifactorial symptomatology of hypereosinophilic diseases
Categories: Drugs for Obstructive Airway DiseasesProducts: NUCALA POWDER FOR SOLUTION FOR INJECTION 100mg, Nucala 100mg Powder for Solution for InjectionAluminum zirconium octachlorohydrex gly
go.drugbank.com/drugs/DB11200ApprovedThe anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows the inclusion of this substance in concentrations of up to 20% in antiperspirants [L2012].
Mixtures: Secret Fresh For You Luxe Lavender, Secret Fresh For You Luxe LavenderProducts: Gillette Hydra Aloe, Gillette Odor Shield All Day CleanAlbutrepenonacog alfa
go.drugbank.com/drugs/DB13884ApprovedAlbutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada ...
Products: IDELVION POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500IU/VIAL, IDELVION POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000IU/VIAL