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Sabatolimab
go.drugbank.com/drugs/DB16322InvestigationalSabatolimab is under investigation in clinical trial NCT03946670 (A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic
Synonyms: Immunoglobulin g4 (226-proline,de-c-terminal-lysine), anti-(human hepatitis virus a cellular receptor 2) (human-mus musculus monoclonal clone nvs260714 .gamma.4-chain), disulfide with human-mus musculusSulfasalazine
go.drugbank.com/drugs/DB00795ApprovedInvestigational[A255582] Sulfasalazine fell out of favor as the drug of choice for RA due to poorly designed clinical trials in 1950 but regained interest from the clinical community in the late 1970. … Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs.
International brands: Saaz-DS, Pyralin ENProducts: SAZO EN TABLETS 500 mg, SARIDINE - EBisacodyl
go.drugbank.com/drugs/DB09020ApprovedInvestigational[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300]
Mixtures: BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADETInternational brands: Reliable Gentle Laxative TabletsSodium hydroxide
go.drugbank.com/drugs/DB11151ApprovedThe use of this compound has been shown to effectively reduce prion levels in an in vitro inactivation assay [A32334]. … Interestingly, sodium hydroxide has been studied for its use in the treatment of prion disease (as occurs in mad cow disease and kuru).
Mixtures: AMINOPLASMAL® 10% E, AMINOPLASMAL® 10% ECategories: Compounds used in a research, industrial, or household settingDivarasib
go.drugbank.com/drugs/DB17488InvestigationalSynonyms: 1-((3S)-4-((7M)-7-(6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((2S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-onePrednisone
go.drugbank.com/drugs/DB00635ApprovedInvestigationalVet approved[A187463] It is biologically inert and converted to [prednisolone] in the liver.[L10502] Prednisone was granted FDA approval on 21 February 1955.[L10496]
Products: LODOTRA®2MG TABLETAS DE CRONO LIBERACIÓN MODIFICADA, LODOTRA®5MG TABLETAS DE CRONO LIBERACIÓN MODIFICADAFlutamide
go.drugbank.com/drugs/DB00499ApprovedInvestigationalAn antiandrogen with about the same potency as cyproterone in rodent and canine species.
Products: ETACONIL DE 250 MG COMPRIMIDOS, FLUTAMIDE EGLamotrigine
go.drugbank.com/drugs/DB00555ApprovedInvestigationalWhile it is indicated for epilepsy and bipolar disorders, there is evidence that lamotrigine could have some clinical efficacy in certain neuropathic pain states.[A849,A850] … Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder.
Products: LAMOTRIGINA EG, Lamotrigine ERTrametes versicolor fruiting body
go.drugbank.com/drugs/DB14287InvestigationalTrametes versicolor fruiting body is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Products: SOMA Heart-Q, SOMA DiatDuvakitug
go.drugbank.com/drugs/DB19444InvestigationalDuvakitug is under investigation in clinical trial NCT05668013 (A Study to Evaluate the Long-term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease).
Synonyms: Du vakitug, Immunoglobulin G1 [de-449-lysine], anti-(human tumor necrosis factor superfamily protein TNFSF15) (human monoclonal TEV-48574 γ1-chain), disulfide with human monoclonal TEV-48574 λ-chain, dimer