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Lidocaine
go.drugbank.com/drugs/DB00281ApprovedInvestigationalVet approvedAs a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L5930, L5948, F4468]. … Regardless, lidocaine is currently available as a relatively non-expensive generic medication that is written for in millions of prescriptions internationally on a yearly basis.
Mixtures: DENTINOX 3.4 MG/G + 3.2 MG/G + 150 MG/G JEL, 10 G, DENTINOX 3.4 MG/G + 3.2 MG/G + 150 MG/G JEL, 20 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsPravastatin
go.drugbank.com/drugs/DB00175ApprovedInvestigationalIt was the first statin administered as the active form and not as a prodrug.[T274] This drug was developed by Sankyo Co. … [L6142] Pravastatin is made through a fermentation process in which [mevastatin] is first obtained.
Products: Nu-pravastatin Tablets, Ag-pravastatinEtodolac
go.drugbank.com/drugs/DB00749ApprovedInvestigationalVet approvedEtodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. … Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Mixtures: S-ETODUO 150/300 MG FİLM KAPLI TABLET, 10 ADET, S-ETODUO 150/500 MG FİLM KAPLI TABLET, 10 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesLoperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigational[A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss. … [A251610] Loperamide has a chemical structure that is similar to diphenoxylate and haloperidol;[A6249] however, loperamide works on mu (μ)-opioid receptors to mediate its pharmacological actions.
Mixtures: Dg Health Anti Diarrheal Anti GasCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesDiazepam
go.drugbank.com/drugs/DB00829ApprovedIllicitInvestigationalVet approvedIt is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal … A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: VALIUM ROCHE AMPOLLAS DE 10 MG / 2 ML., NYX DKetorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigationalKetorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. … [L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511]
Mixtures: Ixoba M, ONEMER DTCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesDuloxetine
go.drugbank.com/drugs/DB00476ApprovedInvestigationalDuloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … [A178741] Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: DU-TWO ® 30 MG, DU-TWO ® 60 MGEthanol
go.drugbank.com/drugs/DB00898ApprovedInvestigationalIt is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. … A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant.
Mixtures: Defense AG Disinfectant, Auto 157Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesDesloratadine
go.drugbank.com/drugs/DB00967ApprovedInvestigationalDesloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. … It is the active descarboethoxy metabolite of loratidine (a second generation histamine).
Mixtures: DELOFED MR 2.5/120 MG KAPSUL, 10 ADET, DELODAY PLUS 120 MG/2,5 MG EFERVESAN TABLET, 10 ADETProducts: EZCLOREN D 5 MG TABLETAS, UNI EFECTINE ® D 5 MG TABLETASTrimebutine
go.drugbank.com/drugs/DB09089ApprovedInvestigationalTrimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. … Trimebutine is not a FDA-approved drug, but it is available in Canada and several other international countries.
Mixtures: RECBUTIN 120 MG/10 MG SUPOZITUVAR, 10 ADET, TRIMEBUTINA 200 MG + SIMETICONA 120 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates