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Displaying results 2191 - 2200 of 10000 in total
  1. Drug

    Ibrexafungerp

    go.drugbank.com/drugs/DB12471
    Approved

    Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast … [A235414,L34349] Ibrexafungerp was granted FDA approval on 1 June 2021.[L34349]

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: (1S,4AR,6AS,7R,8R,10AR,10BR,12AR,14R,15R)-15-((2R)- 2-AMINO-2,3,3-TRIMETHYLBUTOXY)-1,6A,8,10A-TETRAMETHYL-8- ((2R)-3-METHYLBUTAN-2-YL)-14-(5-(PYRIDIN-4-YL)-1H-1,2,4- TRIAZOL-1-YL)-1,6,6A,7,8,9,10,10A,10B, ,11,12,12A-DODECAHYDRO-2H,4H-1,4A-PROPANOPHENANTHRO
  2. Drug

    (+)-Mefloquine

    go.drugbank.com/drugs/DB05636
    Investigational

    -Mefloquine was under investigation in clinical trial NCT00931697 (Study to Investigate the Safety, Tolerability and Pharmacokinetics of AD 452 [(+)-Mefloquine] Compared With Racemic Mefloquine) to compare

    Synonyms: [(11R,2'S)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol, (+)-(11R,2'S)-erythro-mefloquine
  3. Drug

    Fipaxalparant

    go.drugbank.com/drugs/DB18124
    Investigational

    Synonyms: 1h-indene-2-carboxylic acid, 2,3-dihydro-2-((4-methoxy-3-(2-(3-methylphenyl)ethoxy)benzoyl)amino)-
  4. Drug

    Cinolazepam

    go.drugbank.com/drugs/DB01594
    Investigational

    Cinolazepam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. It is not approved in Canada or America.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 1-(2-cyanoethyl)-7-chloro-3-hydroxy-5-(2'-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-3-hydroxy-2-oxo-1H-1,4-benzodiazepine-1-propanenitrile
  5. Drug

    TPCA-1

    go.drugbank.com/drugs/DB17058
    Experimental

    TPCA-1 is a selective inhibitor of human IκB kinase 2 (IKK-2).[A253152]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: Ikk 2 inhibitor iv, Ikk-2 inhibitor iv
  6. Drug

    NNC-55-0396 free base

    go.drugbank.com/drugs/DB17037
    Experimental

    NNC-55-0396 is a T-type Ca(2+) channel inhibitor.[A253047]

    Synonyms: Cyclopropanecarboxylic acid, (1s,2s)-2-(2-((3-(1h-benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester
  7. Drug

    Manitimus

    go.drugbank.com/drugs/DB06481
    Investigational

    FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: (2Z)-2-cyano-3-3hydroxy-N-[4-(trifluoromethly)phenyl]-2-hepten-6-ynamide, (2Z)-2-CYANO-3-HYDROXY-N-(4-(TRIFLUOROMETHLY)PHENYL)-2-HEPTEN-6-YNAMIDE
  8. Drug

    t-Butylhydroquinone

    go.drugbank.com/drugs/DB07726
    Experimental

    Synonyms: 2-t-Butylhydroquinone, 2-t-Butyl-1,4-benzenediolCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Chlorthalidone

    go.drugbank.com/drugs/DB00310
    ApprovedInvestigational

    These pathways may play a role in chlorthalidone's cardiovascular risk reduction effects.[A176330] … Chlorthalidone has been shown to have a number of pleiotropic effects that differentiate it from other diuretics such as [DB00999].

    Mixtures: TENORETIC 100 MG/25 MG FILM TABLET, 28 ADET, BRASARTAN® CTDN 160/25 MGCategories: Heterocyclic Compounds, 2-Ring
  10. Drug

    Chlorophetanol

    go.drugbank.com/drugs/DB11368
    Experimental

    Chlorophetanol is an agent known to have antifungal activities.

    Synonyms: 2-(4-Chlorophenoxy)ethanol, 2-(4-chlorphenoxy)-ethanolCategories: 2-(4-chlorphenoxy)-ethanol