Search

Displaying results 2191 - 2200 of 4190 in total
  1. Drug

    Diethylstilbestrol

    go.drugbank.com/drugs/DB00255
    ApprovedWithdrawn

    According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen.

  2. Drug

    Diflunisal

    go.drugbank.com/drugs/DB00861
    Approved

    Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the arachidonic acid pathway.

  3. Drug

    GTP-506

    go.drugbank.com/drugs/DB17682
    Experimental

    GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide

  4. Drug

    Lusutrombopag

    go.drugbank.com/drugs/DB13125
    ApprovedInvestigational

    TPOR is a regulatory target site for endogenous thrombopoietin, which acts as a primary cytokine to promote megakaryocyte proliferation and differentiation, and affect other hematopoietic lineages as well

  5. Drug

    ORG-34517

    go.drugbank.com/drugs/DB05423
    Investigational

    ORG-34517 is currently under investigation by Organon for the treatment of depression. It has potential to treat a number of diseases such as Cushing’s disease, hypertension, diabetes, glaucoma etc, in which the activity of metabolites c...

  6. Drug

    5-androstenedione

    go.drugbank.com/drugs/DB01456
    ExperimentalIllicit

    from the positioning of a carbon-carbon double bond, its structure is similar to [4-androstenedione], which is a prohormone which is naturally produced in the body by the adrenal glands and gonads, and acts

  7. Drug

    Tymazoline

    go.drugbank.com/drugs/DB08803
    Experimental

    Tymazoline is a nasal preparation.

  8. Drug

    Human Interleukin 8

    go.drugbank.com/drugs/DB16456
    Investigational

    Interleukin-8 is under investigation in clinical trial NCT05148234 (BMS-986253 in Myelodysplastic Syndromes).

  9. Drug

    Biotin

    go.drugbank.com/drugs/DB00121
    ApprovedInvestigationalNutraceutical

    A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.

    Mixtures: GNC Mega Teen, BLACKMORES teen multi for GUYS capsule
  10. Target

    Galectin-7

    go.drugbank.com/bio_entities/BE0001008
    TargetHumans

    Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release

    Synonyms: p53-induced gene 1 protein