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Cretostimogene grenadenorepvec
go.drugbank.com/drugs/DB05148InvestigationalCG0070 can potentially destroy cancer cells by two different mechanisms: direct cell killing by the virus and immune-mediated cell killing stimulated by GM-CSF.
Vemurafenib
go.drugbank.com/drugs/DB08881ApprovedInvestigational[A31269] It exerts its function by binding to the ATP-binding domain of the mutant BRAF. … [A31270] Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann La Roche.
Clevudine
go.drugbank.com/drugs/DB06683InvestigationalCategories: Antivirals for Systemic Use, Antiinfectives for Systemic UseSomatrogon
go.drugbank.com/drugs/DB14960ApprovedInvestigational[L39060] In June 2023, the FDA approved the use of somatrogon also for the treatment of pediatric growth hormone deficiency. … Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood
Trimethadione
go.drugbank.com/drugs/DB00347ApprovedWithdrawnAn anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
Influenza B virus B/Darwin/7/2019 antigen (MDCK cell derived, propiolactone inactivated)
go.drugbank.com/drugs/DB15709ApprovedWithdrawnVaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
Polihexanide
go.drugbank.com/drugs/DB12277ApprovedInvestigational[A1351,A273908] Polihexanide is approved in Europe under the name Akantior for the treatment of _Acanthamoeba_ keratitis, an ocular infection caused by the _Acanthamoeba_ parasite. … Structurally, it consists of repeating biguanide units linked by hexamethylene hydrocarbon chains, conferring both hydrophilic and hydrophobic properties that enhance its interaction with microbial membranes
Terazosin
go.drugbank.com/drugs/DB01162ApprovedInvestigationalTerazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label] . Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing rela...
Flurbiprofen
go.drugbank.com/drugs/DB00712ApprovedInvestigationalFlurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, os...
Categories: Antiinflammatory Preparations, Non-Steroids for Topical UseAC-100
go.drugbank.com/drugs/DB05671InvestigationalIt is being developed by Acologix, Inc. … AC-100 is a novel synthetic peptide derived from an endogenous human protein produced by bone and dental cells (a fragment from matrix extracellular phosphoglycoprotein).