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Olopatadine
go.drugbank.com/drugs/DB00768ApprovedOlopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine work...
NNZ-2591
go.drugbank.com/drugs/DB15601InvestigationalNNZ-2591 (cyclo-L-glycyl-L-2-allylproline)[A189390] is an investigational synthetic analog of cyclic glycine-proline (cGP), a breakdown product of human insulin-like growth factor 1 (IGF-1), that has been
Trovafloxacin
go.drugbank.com/drugs/DB00685ApprovedWithdrawnTrovafloxacin is a broad spectrum antibiotic that has been commonly marketed under the brand name Trovan by Pfizer.
Dabrafenib
go.drugbank.com/drugs/DB08912ApprovedInvestigational[L41955] In May 2018, Tafinlar (dabrafenib), in combination with Mekinist ([DB08911]), was approved to treat anaplastic thyroid cancer caused by an abnormal BRAF V600E gene.[L41955]
Von Willebrand factor human
go.drugbank.com/drugs/DB13133ApprovedInvestigationalThe human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the sit...
Sacituzumab govitecan
go.drugbank.com/drugs/DB12893ApprovedInvestigationalMetastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited treatment options involving cytotoxic chemotherapy agents. Targeted chemotherapy through the application of antibody-conjugated agents (...
Glofitamab
go.drugbank.com/drugs/DB16371ApprovedInvestigationalGlofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- and T-cells, respectively. It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, a...
Zinc gluconate
go.drugbank.com/drugs/DB11248ApprovedInvestigationalVet approvedAlthough it has been nasally administered for treating the common cold, this route of administration has been associated with some cases of anosmia [A32414], [A32409], [A32410], [L2080].