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Displaying results 2201 - 2210 of 4859 in total
  1. Drug

    Aloe vera leaf

    go.drugbank.com/drugs/DB13906
    ApprovedInvestigational

    It is a perennial succulent xerophyte with elongated leaves that contain a clear gel. … While aloe vera has a long history of commercial uses, it is still widely used in cosmetic, food and pharmaceutical products.

  2. Drug

    Estradiol dienanthate

    go.drugbank.com/drugs/DB13955
    ApprovedVet approvedWithdrawn

    First-pass metabolism by the gut and the liver quickly degrades the estradiol molecule before it gets a chance to enter systemic circulation and exert its estrogenic effects [A12102].

  3. Drug

    Deramciclane

    go.drugbank.com/drugs/DB06512
    Investigational

    It antagonizes 5-HT2A receptors, agonizes 5-HT2C receptors, and functions as a GABA reuptake inhibitor. … Deramciclane differs from other anti anxiety medications in that it is not a benzodiazepine and so has a different structure and target.

  4. Drug

    Pimethixene

    go.drugbank.com/drugs/DB13292
    Approved

    It is an anticholinergic used in the treatment of bronchitis.

  5. Drug

    Etilefrine

    go.drugbank.com/drugs/DB08985
    ApprovedWithdrawn

    It has been used as a vasoconstrictor agent.

  6. Drug

    Canrenoic acid

    go.drugbank.com/drugs/DB09015
    ApprovedInvestigationalWithdrawn

    Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body.

  7. Drug

    Teplizumab

    go.drugbank.com/drugs/DB06606
    ApprovedInvestigational

    Although the mechanism of action of teplizumab has not been fully elucidated, it may involve partial agonistic signaling and deactivation of pancreatic beta cell autoreactive T lymphocytes.

  8. Drug

    Dronedarone

    go.drugbank.com/drugs/DB04855
    ApprovedInvestigational

    It is managed by rate control, rhythm control, prevention of thromboembolic events, and treatment of the underlying disease. … [A186071] It meets criteria of all four Vaughan Williams antiarrhythmic drug classes by blocking sodium, potassium, and calcium ion channels and inhibiting β-adrenergic receptors.

  9. Drug

    Laronidase

    go.drugbank.com/drugs/DB00090
    ApprovedInvestigational

    It contains 6 N-linked oligosaccharide modification sites. … The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human a-L-iduronidase.

  10. Drug

    Clidinium

    go.drugbank.com/drugs/DB00771
    Approved

    It inhibits muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites. … It is used for the treatment of peptic ulcer disease and also to help relieve abdominal or stomach spasms or cramps due to colicky abdominal pain, diverticulitis, and irritable bowel syndrome.