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Displaying results 2201 - 2210 of 10000 in total
  1. Drug

    OBI-3424

    go.drugbank.com/drugs/DB16057
    Investigational

    OBI-3424 is under investigation in clinical trial NCT04315324 (Study to Test Akr1c3-activated Prodrug OBI-3424 (OBI-3424) in Patients With Relapsed/refractory T-cell Acute Lymphoblastic Leukemia (T-ALL

    Synonyms: 3-(5-((1R)-1-(Bis(aziridin-1-yl(phosphoryloxy)ethyl)-2-nitrophenoxy)-N,N-dimethylbenzamide, 3-[5-[(1R)-1-[bis(aziridin-1-yl(phosphoryloxy]ethyl]-2-nitrophenoxy]-N,N-dimethylbenzamide
  2. Drug

    Dexamethasone

    go.drugbank.com/drugs/DB01234
    ApprovedInvestigationalVet approved

    Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic … [L10695] In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 June 2020, dexamethasone was recommended for use in COVID-19 patients with severe respiratory symptoms

    Synonyms: 16α-Methyl-9α-fluoro-1-dehydrocortisol, 1-Dehydro-16α-methyl-9α-fluorohydrocortisoneMixtures: NETİZON 5 MG+15 MG/5 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, VITATRIOL (NEOMICINA 3.5 MG + POLIMIXINA B SULFATO 6000 U.I. + DEXAMETASONA 1 MG)/1ML
  3. Drug

    Elinzanetant

    go.drugbank.com/drugs/DB18968
    ApprovedInvestigational

    Elinzanetant is a non-hormonal, selective, dual neurokinin 1 (NK-1) and 3 (NK-3) receptor antagonist. … [L53798] By blocking receptor signaling on kisspeptin/neurokinin B/dynorphin (KNDy) neurons, which are hyperactivated due to estrogen decline in menopause, elinzanetant modulates neuronal activity involved

    Synonyms: Benzamide, 3-(5-methyl-2-tbenzeneacetamide, n-(4-(4-fluoro-2-methylphenyl)-6-((7s,9as)-hexahydro-7-(hydroxymethyl)pyrazino(2,1-c)(1,4)oxazin-8(1h)-yl)-3-pyridinyl)-n,.alpha.,.alpha., 2-(3,5-bis(trifluoromethyl)phenyl)-n-(4-(4-fluoro-2-methylphenyl)-6-((7s,9as)-7-(hydroxymethyl)hexahydropyrazino(2,1-c)(1,4)oxazin-8(1h)-yl)-3-pyridinyl)-n,2-dimethylpropanamideCategories: Neurokinin 1 Antagonists, Heterocyclic Compounds, 1-Ring
  4. Drug

    Tobramycin

    go.drugbank.com/drugs/DB00684
    ApprovedInvestigational

    such as β-lactams and cephalosporins. … [A232294, A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a variety of forms for administration by inhalation, injection, and external application to

    Mixtures: TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET, OFTAMYCİN-DX % 0.3 + % 0.1 GÖZ DAMLASI, ÇÖZELTİ, 5 ML, 1 ŞİŞECategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
  5. Drug

    Dopamine

    go.drugbank.com/drugs/DB00988
    ApprovedInvestigational

    It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. … A family of receptors (receptors, dopamine) mediate its action.

    Mixtures: Dopamine HCl 3.2mg/ml Dextrose 5% Inj USP, Dopamine HCl 1.6mg/ml Dextrose 5% Inj USPCategories: Selective Beta 1-adrenergic Agonists, Adrenergic and Dopaminergic Agents
  6. Drug

    Ampicillin

    go.drugbank.com/drugs/DB00415
    ApprovedInvestigationalVet approved

    Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.

    Mixtures: BACTAMED 500 MG/250 MG IM IV ENJEKTABL TOZ IÇEREN FLAKON, 10 ADET, AZOSILIN 500 MG/50 MG TABLET, 12 ADETCategories: Penicillin G, Heterocyclic Compounds, 2-Ring
  7. Drug

    Baclofen

    go.drugbank.com/drugs/DB00181
    ApprovedInvestigational

    [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977. … Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant.

    Synonyms: 4-Amino-3-(4-chlorophenyl)butyric acid, DL-4-Amino-3-p-chlorophenylbutanoic acidMixtures: Innoprax-5
  8. Drug

    Benzyl N-[(2S)-5-(diaminomethylamino)-1-[[(2S)-4-fluoro-3-oxobutan-2-yl]amino]-1-oxopentan-2-yl]carbamate

    go.drugbank.com/drugs/DB03536
    Experimental

    Synonyms: Benzyl N-[(2S)-5-(diaminomethylamino)-1-[[(2S)-4-fluoro-3-oxobutan-2-yl]amino]-1-oxopentan-2-yl]carbamate
  9. Drug

    Levocarnitine

    go.drugbank.com/drugs/DB00583
    ApprovedInvestigational

    Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.

    Mixtures: Q 10 Suprabio +L-Carnitine, Nutriforte Q10 PlusCategories: Amino Acids and Derivatives, Alimentary Tract and Metabolism
  10. Drug

    Bemnifosbuvir

    go.drugbank.com/drugs/DB19050
    Investigational

    Bemnifosbuvir is under investigation in clinical trial NCT05629962 (SUNRISE-3: Efficacy and Safety of Bemnifosbuvir in High-risk Outpatients With COVID-19).

    Categories: Heterocyclic Compounds, 2-Ring, Nucleic Acids, Nucleotides, and NucleosidesSynonyms: N-((p(s),2'r)-2-amino-2'-deoxy-2'-fluoro-n,2'-dimethyl-p-phenyl-5'-adenylyl)-l-alanine 1-methylethyl ester, L-alanine, n-((p(s),2'r)-2-amino-2'-deoxy-2'-fluoro-n,2'-dimethyl-p-phenyl-5'-adenylyl)-, 1-methylethyl ester