Search
Desipramine
go.drugbank.com/drugs/DB01151ApprovedThe antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. … In depressed individuals, desipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Combined Inhibitors of Serotonin/Norepinephrine ReuptakeSynonyms: N-(3-methylaminopropyl)iminobibenzyl, DMIBrexpiprazole
go.drugbank.com/drugs/DB09128ApprovedInvestigationalBrexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM). … Compared to aripiprazole, brexpiprazole has less potential for partial agonist-mediated adverse effects such as extrapyramidal symptoms, which is attributed to lower intrinsic activity at the D2 receptor
Categories: Dopamine D2 Receptor Agonists, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: REXULTI (BREXPIPRAZOLE) TABLETS 1 MG, REXULTI (BREXPIPRAZOLE) TABLETS 2 MGThioridazine
go.drugbank.com/drugs/DB00679ApprovedWithdrawnA phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. … Thioridazine was withdrawn worldwide in 2005 due to its association with cardiac arrythmias.
Synonyms: 3-Methylmercapto-N-(2'-(N-methyl-2-piperidyl)ethyl)phenothiazine, 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazineInternational brands: Mellaril-SLanadelumab
go.drugbank.com/drugs/DB14597ApprovedInvestigationalLanadelumab, also known as DX-2930, is a human IgG1 monoclonal antibody designed for subcutaneous self-injection. … [L4538] It is a fully human immunoglobulin, k-light-chain made in recombinant Chinese Hamster Ovary cells.
Categories: Drugs Used in Hereditary AngioedemaProducts: TAKHZYRO 300 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, TAKHZYRO 300 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADETLifitegrast
go.drugbank.com/drugs/DB11611ApprovedInvestigationalIt has shown to protect the corneal surface and alleviate the symptoms of dry eye syndrome with fast onset of action and well tolerated profile in both local and systemic setting [A18805]. … The ophthalmic solution was approved in July, 2016 under the trade name Xiidra.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP2C9 InhibitorsTasosartan
go.drugbank.com/drugs/DB01349ExperimentalTasosartan is a long-acting angiotensin II (AngII) receptor blocker. Its long duration of action has been attributed to its active metabolite enoltasosartan. … It is used to treat patients with essential hypertension.
Categories: Angiotensin II receptor blockers (ARBs), plain, Agents Acting on the Renin-Angiotensin SystemGlutathione
go.drugbank.com/drugs/DB00143ApprovedInvestigationalNutraceuticalA tripeptide with many roles in cells. … It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
Mixtures: VitaHealth L-Glutathione Plus, Essential Pro ALPHA-G Q10 CapsuleSynonyms: N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine, 5-L-Glutamyl-L-cysteinylglycineSodium zirconium cyclosilicate
go.drugbank.com/drugs/DB14048ApprovedInvestigationalthe median time to achieving normal potassium levels in the blood was 2.2 hours, with 92% of patients achieving normal potassium levels within 48 hours following administration. … [L2933] Approval of the medication is supported by data from three double-blind, placebo-controlled trials and two open-label trials which showed that the onset of action was approximately 1.0 hour and
Categories: Compounds used in a research, industrial, or household setting, Ion Exchange ResinsProducts: SIMKELMA 5 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 28 ADET, SIMKELMA 5 G ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 11 ADETPrimidone
go.drugbank.com/drugs/DB00794ApprovedVet approved[L11112] Primidone was developed by J Yule Bogue and H C Carrington in 1949.[A189522] Primidone was granted FDA Approval on 8 March 1954.[L11112] … Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures.
Categories: combinations of barbiturates, Cytochrome P-450 SubstratesSynonyms: 5-Phenyl-5-ethyl-Hexahydropyrimidine-4,6-dione, 2-deoxyphenobarbitalGallium Ga-68 gozetotide
go.drugbank.com/drugs/DB16019ApprovedInvestigationalprostate cancer or in patients who may have recurrent prostate cancer. … [L43542] In December of the same year, the drug was fully authorized by the EMA.[L44682] In Octer 2022, Ga-68 PSMA-11 was approved by Health Canada for diagnostic use in men with prostate cancer.
Synonyms: (68)Ga Labeled Glu-NH-CO-NH-Lys(ahx)-hbed-CCCategories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of Chemicals