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Iodine povacrylex
go.drugbank.com/drugs/DB09537ApprovedIt is a broad spectrum antiseptic and can provide almost 99.9% antiseptic conditions. It is intended for local use only. … DuraPrep solution is indicated for use as a patient preoperative skin preparation, for the preparation of the skin prior to surgery and to help reduce bacteria that can potentially cause skin infection
Gefapixant
go.drugbank.com/drugs/DB15097ApprovedIt has been estimated that 5-10% of adults globally suffer from chronic cough, which is defined as a cough lasting longer than eight weeks. … [L48596,L48591] It is the first therapy to be approved for the treatment of RCC or UCC in the EU.[L48601]
Givinostat
go.drugbank.com/drugs/DB12645ApprovedInvestigationalIt has been investigated as a treatment for a variety of inflammatory diseases, like Crohn's disease and juvenile idiopathic arthritis, cancers like leukemia and lymphoma, as well as several muscular dystrophies … [L50311,L50316] It is the first non-steroidal drug approved to treat patients with all genetic variants of DMD.[L50316]
Udenafil
go.drugbank.com/drugs/DB06267ApprovedUdenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena. … It is not yet approved for use in the U.S., E.U., or Canada.
Netarsudil
go.drugbank.com/drugs/DB13931ApprovedInvestigationalActing as both a rho kinase inhibitor and a norepinephrine transport inhibitor, Netarsudil is a novel glaucoma medication in that it specifically targets the conventional trabecular pathway of aqueous … humour outflow to act as an inhibitor to the rho kinase and norepinephrine transporters found there as opposed to affecting protaglandin F2-alpha analog like mechanisms in the unconventional uveoscleral
Pemirolast
go.drugbank.com/drugs/DB00885ApprovedWithdrawnIt is a mast cell stabilizer that acts as an antiallergic agent. … As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis.
Omaveloxolone
go.drugbank.com/drugs/DB12513ApprovedInvestigationalTherefore, the use of Nrf2 activators such as omaveloxolone represents a therapeutic advantage in this group of patients. … [A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a transcription factor that mitigates oxidative stress.
Riltozinameran
go.drugbank.com/drugs/DB17095ApprovedInvestigational[L43917] As of November 2022, it is the primary circulating variant of concern according to the World Health Organization. … The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021.
Artenimol
go.drugbank.com/drugs/DB11638ApprovedInvestigationalIt was first authorized for market by the European Medicines Agency in October 2011 in combination with [DB13941] as the product Eurartesim.
Teriparatide
go.drugbank.com/drugs/DB06285ApprovedInvestigational[A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH.