Search
Peginterferon beta-1a
go.drugbank.com/drugs/DB09122ApprovedInvestigationalIt was originally approved by the FDA in 2014 for subcutaneous use, and was approved for intramuscular use in January 2021. … [L31428] Currently, it is the only approved pegylated interferon for the management of MS with an proven ability to reduce relapses and delay the progression of disability resulting from MS.
Butyrfentanyl
go.drugbank.com/drugs/DB09173ExperimentalIllicit[L7811] This compound is a schedule I controlled substance in the USA because it is a positional isomer of 3-Methylfentanyl. … [L7814] The DEA in the United States has confirmed at least 40 fatalities involving butyrfentanyl before May 2016.[L7811]
Modafinil
go.drugbank.com/drugs/DB00745ApprovedInvestigationalThe exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lead to an increase in extracellular
Products: VIGIA® 100 MG, VIGIA ®200 MGThioridazine
go.drugbank.com/drugs/DB00679ApprovedWithdrawn(From Martindale, The Extra Pharmacopoeia, 30th ed, p618). Thioridazine was withdrawn worldwide in 2005 due to its association with cardiac arrythmias. … It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine.
Products: RIDAZINE (TABLET 25 MG), RIDAZINE (25 MG TABLET)Tasonermin
go.drugbank.com/drugs/DB11626ApprovedIt is administered with [DB01042] via mild hyperthermic isolated limb perfusion. … It was approved for use by the European Medicines Agency in April of 1999 for use as an adjunt to surgery for the subsequent removal of the tumor and in palliative care for irresectable soft tissue sarcoma
Vutrisiran
go.drugbank.com/drugs/DB16699ApprovedInvestigational[A249010] More than 130 TTR mutations have been identified so far,[A249015] but the most common one is the replacement of valine with methionine at position 30 (Val30Met).
Anileridine
go.drugbank.com/drugs/DB00913ApprovedIllicitWithdrawnIt is a narcotic pain reliever used to treat moderate to severe pain. Narcotic analgesics act in the central nervous system (CNS) to relieve pain.
Amylocaine
go.drugbank.com/drugs/DB09088ApprovedWithdrawnAlthough amylocaine could be administered topically or injected, it was most widely used for spinal anesthesia [L1882]. … Elsewhere in English speaking countries it was referred to as Stovaine, given the meaning of the French word 'fourneau' as 'stove' in English [L1882].
Technetium Tc-99m disofenin
go.drugbank.com/drugs/DB09164ApprovedWithdrawnIt is available as an intravenous injection in a preparation kit under the name Hepatolite. … Technetium Tc-99m is a metastable nuclear isomer and disofenin is an iminodiacetic acid derivative with no known pharmacologic actions at the doses recommended.