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Eladocagene exuparvovec
go.drugbank.com/drugs/DB16780ApprovedInvestigationaland rare genetic disorder that causes severe disability in pediatric patients. … Eladocagene exuparvovec is a recombinant adeno-associated virus-2 (AAV2)-based gene therapy that expresses human aromatic L-amino acid decarboxylase (AADC), and it is used to treat AADC deficiency, a fatal
Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismHuman botulinum neurotoxin A/B immune globulin
go.drugbank.com/drugs/DB14115Approved[L39834] It is produced and distributed by the Calfornia Department of Public Health's Infant Botulism Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma … from persons immunized with recombinant botulinum vaccine who have high titers of neutralizing antibodies against botulinum toxin.
Difamilast
go.drugbank.com/drugs/DB14987ApprovedInvestigationalAtopic dermatitis is a chronic and fluctuating pruritic inflammatory skin condition characterized by pruritic eczema and is also marked by exacerbations and remissions. … The drug is indicated for the topical treatment of mild to moderate atopic dermatitis in adults and pediatric patients 2 years of age and older [L55042]. It is approved in Japan and the United States.
Categories: Benzamides and benzamide derivativesYellow fever vaccine
go.drugbank.com/drugs/DB10805ApprovedInvestigationalInterestingly, Yellow fever got its name from the characteristic yellowing of the skin and eyes that occurs from the development of jaundice when the virus attacks the liver. … Symptoms of Yellow fever can range from asymptomatic, to mild flu-like illness, to more severe symptoms such as shock, jaundice, internal bleeding, and organ failure [L1655].
Products: STAMARIL Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension Gelbfieber - LebendimpfstoffQuinine
go.drugbank.com/drugs/DB00468ApprovedInvestigationalAn alkaloid derived from the bark of the cinchona tree. … It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.
Categories: Quinine and stereoisomer, Antiparasitic Products, Insecticides and RepellentsElranatamab
go.drugbank.com/drugs/DB15395ApprovedInvestigationalIt is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one … [L47820] Elranatamab was also approved by the European Commission on December 8, 2023.[L50437]
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsArtenimol
go.drugbank.com/drugs/DB11638ApprovedInvestigationalArtemisinin combination therapy is highly effective against malaria and stongly recommended by the World Health Organization [L1156]. … Artenimol is an artemisinin derivative and antimalarial agent used in the treatment of uncomplicated *Plasmodium falciparum* infections [FDA Label].
Categories: Artemisinin and derivatives, artenimol and piperaquineMeticillin
go.drugbank.com/drugs/DB01603ApprovedInvestigationalOne of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
Isavuconazole
go.drugbank.com/drugs/DB11633ApprovedInvestigationalIt is approved by the FDA and EMA for the treatment of invasive aspergillosis and mucormycosis. It works by inhibiting fungal cell membrane synthesis. … It is proposed that the intravenous and oral dosing can be used interchangeably [L1482], without the need for a repeat loading dose when transitioning from an IV to an oral formulation [A32026].
Categories: Isavuconazole and Prodrugs, Triazole and tetrazole derivatives