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Aducanumab
go.drugbank.com/drugs/DB12274ApprovedInvestigational[L34420] Biogen enrolled patients in phase 3 clinical trials in 2015 but increased the size of the trials from 1350 patients to 1650 patients to maintain statistical power in the face of a high standard … [A235668,A235720] Clinical trials showed a 23% relative difference between the experimental and placebo groups as determined by CDR; however, this is equivalent to an absolute difference of 0.4/18.
Lorcaserin
go.drugbank.com/drugs/DB04871ApprovedInvestigationalWithdrawnIn February 2020, the FDA issued a Drug Safety Communication requesting the manufacturer of Belviq (lorcaserin hydrochloride tablets, 10 mg) and Belviq XR (lorcaserin hydrochloride extended-release tablets … , 20 mg) to voluntarily withdraw these products from the U.S. market, and the company has submitted a request to voluntarily withdraw the drug.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT2 Receptor AgonistsErtapenem
go.drugbank.com/drugs/DB00303ApprovedInvestigational[A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to treat various bacterial infections. … Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics.[L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002.
Synonyms: (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acidProducts: EKİPERTA 1 G İM/İV ENJEKSİYON İÇİN LİYOFİLİZE TOZ, INVANZ 1 G IM/IV ENEJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADETDexchlorpheniramine
go.drugbank.com/drugs/DB13679InvestigationalIt disrupts histamine signaling by competing with histamine for cell receptor sites on effector cells.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: POLARAMINE TABLETAS 3 MGCinolazepam
go.drugbank.com/drugs/DB01594InvestigationalCinolazepam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. It is not approved in Canada or America.
Synonyms: 7-chloro-5-(o-fluorophenyl)-2,3-dihydro-3-hydroxy-2-oxo-1H-1,4-benzodiazepine-1-propionitrile, 1-(2-cyanoethyl)-7-chloro-3-hydroxy-5-(2'-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-oneProducts: Gerodorm 40 mg - TablettenInfection and inflammatory reaction due to internal prosthetic device, implant, and graft
go.drugbank.com/conditions/DBCOND0089198Drugs: CefadroxilSynonyms: Infection and inflammatory reaction due to internal prosthetic device, implant, and graftBesifloxacin
go.drugbank.com/drugs/DB06771ApprovedBesifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. FDA approved on May 28, 2009.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: BESIVANCE % 0,6 OFTALMIK SÜSPANSIYON, 5 MLTechnetium Tc-99m sulfur colloid
go.drugbank.com/drugs/DB09397ApprovedThis is possible as Technetium-99m decays by isomeric transition to technetium-99 through the release of a gamma ray. … Following injection or oral administration, single photon emission computer tomography (SPECT) imaging is performed using a gamma camera to detect technetium-99m decay.
Synonyms: Technetium Tc 99m sulfur colloid, Technetium Tc-99m Sulfur ColloidProducts: Kit for the Preparation of Technetium Tc 99m Sulfur ColloidAPT-101
go.drugbank.com/drugs/DB18003ExperimentalSynonyms: (S)-3-(1-Cyclopentyl-5-(2-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxamido)-5-(3,3-difluoropiperidin-1-yl)pentanoic acidSalts: APT-101 hydrochlorideYA-101
go.drugbank.com/drugs/DB18121InvestigationalSynonyms: 5-o-desmethylomeprazole, 5-o-desmethyl omeprazole