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Resmetirom
go.drugbank.com/drugs/DB12914ApprovedInvestigational[L50336] Thyroid hormones directly regulate lipid metabolism in the liver; thus, impaired thyroid function, such as low serum thyroid hormone levels, is often observed in NAFLD. … On March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alcoholic fatty liver disease (NAFLD
Ustilago tritici
go.drugbank.com/drugs/DB10444ApprovedUstilago tritici is a fungus which can provoke allergic reactions. Ustilago tritici extract is used in allergenic testing.
Mixtures: Treatment Set TS329906, Treatment Set TS330370Talc
go.drugbank.com/drugs/DB09511ApprovedInvestigationalTalc is a mineral composed primarily of magnesium, silicon and oxygen. … It is a substance often found in cosmetic and personal hygiene products including baby powder, adult body powders and facial powders.
Mixtures: OHUI Sun Science Sun Block EX plus BeigeCategories: Compounds used in a research, industrial, or household settingPhoma destructiva
go.drugbank.com/drugs/DB10813ApprovedPhoma destructiva is a fungus which can provoke allergic reactions. Phoma destructiva extract is used in allergenic testing.
Mixtures: A Mold Mixture, A Mold MixtureNiclosamide
go.drugbank.com/drugs/DB06803ApprovedInvestigationalVet approvedNiclosamide is an antihelminthic used for the treatment of tapeworm infections. … They are an even greater problem in domestic animals. Niclosamide, once marketed in the US under the brand name Niclocide, was voluntarily withdrawn from market by Bayer in 1996.[L11860]
Categories: Compounds used in a research, industrial, or household settingProducts: TENYADÜŞ TABLET, 4 ADET, YOMESAN 500 MG TABLET, 4 ADETPimozide
go.drugbank.com/drugs/DB01100ApprovedA diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. … Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexProducts: NOROFREN 2 MG TABLET, 10 ADET, NOROFREN 2 MG TABLET, 20 ADETArticaine
go.drugbank.com/drugs/DB09009ApprovedInvestigationalArticaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Mixtures: SEPTANEST® ADRENALINEE AU 1/100.000, ARTHEEK(R) ARTICAINA AL 4% CON EPINEFRINA 1:100.000Cinnamyl alcohol
go.drugbank.com/drugs/DB14186ApprovedDue to the low levels found in cinnamon, cinnamyl alcohol is usually supplied as [DB14184] within commercial products. … Cinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% [A34266]. Sensitivity to cinnamyl alcohol may be identified with a clinical patch test.
Docetaxel
go.drugbank.com/drugs/DB01248ApprovedInvestigational[A259676] Compared to paclitaxel, docetaxel is two times more potent as an inhibitor of microtubule depolymerization. Docetaxel binds to microtubules but does not interact with dimeric tubulin. … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel].
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: DOCETAXEL DONG-A, ICEREN FLAKON, 1 ADETCladosporium herbarum
go.drugbank.com/drugs/DB10865ApprovedCladosporium herbarum is a fungus which can provoke allergic reactions. Cladosporium herbarum extract is used in allergenic testing.
Mixtures: Treatment Set TS332229, Treatment Set TS332091