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Diroximel fumarate

This drug is bioequivalent to [Dimethyl fumarate][A187544,L9626](initially manufactured in 2013), but is less likely to cause gastrointestinal side effects, owing to its unique chemical structure. … [A187535] Diroximel fumarate is a new drug from the fumarate class formulated to treat various relapsing forms of MS.

Gliquidone

Gliquidone is a sulfonylurea drug used to treat diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. … This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.

Pralatrexate

[A246703] As such, pralatrexate is thought to have a better therapeutic window compared to other antifolate analogs due to the novel target of RFC. … [A246693] Compared to methotrexate, pralatrexate has better accumulation in cancer cells.

Nedocromil

A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.

Eplontersen

multiple organs, although wild-type misfolded TTR has also been observed to contribute to the disease pathophysiology. … [A262985] As eplontersen targets both the WT and mutant TTR, it poses tremendous promises as a treatment.

Plinabulin

Autologous cultured chondrocytes

Autologous cultured chrondrocytes are used as autologous cell therapy to repair articular cartilage injuries in the knee (femoral condyle) due to acute or repetitive trauma. … It serves as an alternative repair treatment for patients with inadequate response to pre-existing surgical methods.

Terpin hydrate

Elixirs of terpin hydrate are still available to patients as prescription medications to be prepared by specialty compounding pharmacies. … Terpin hydrate is an expectorant, commonly used to loosen mucus and ease congestion in patients presenting with acute or chronic bronchitis, and related pulmonary conditions.

Fluvoxamine

Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder.

Asenapine

Asenapine also belongs to the dibenzo-oxepino pyrrole class. It is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009.